Preparation of an iron porphyrin-based polymer monolithic column via atom transfer radical polymerization for the separation of proteins and small molecules

2017 ◽  
Vol 9 (17) ◽  
pp. 2596-2602 ◽  
Author(s):  
Zhen Wei ◽  
Doudou Zhang ◽  
Cheng Li ◽  
Ligai Bai ◽  
Haiyan Liu ◽  
...  
Keyword(s):  
Atom Transfer Radical Polymerization ◽  
Small Molecules ◽  
Radical Polymerization ◽  
Monolithic Column ◽  
Iron Porphyrin ◽  
Atom Transfer ◽  
Polymer Monolithic Column ◽  
Separation Of Proteins

An iron porphyrin-based polymer monolithic column was prepared via ATRP for the separation of proteins from bio-matrices and small molecules.

Separation of proteins from complex bio-matrix samples using a double-functionalized polymer monolithic column

The Analyst ◽  
2018 ◽  
Vol 143 (1) ◽  
pp. 280-288 ◽  
Author(s):  
Doudou Zhang ◽  
Dandan Lan ◽  
Xiaomin Pang ◽  
Beijiao Cui ◽  
Ligai Bai ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Monolithic Column ◽  
Iron Porphyrin ◽  
Polymer Monolithic Column ◽  
Separation Of Proteins

A double-functionalized polymer monolithic column was fabricated via a facile method using iron porphyrin and ionic liquid as functional co-monomers.

scholarly journals Axially Ligated Mesohemins as Bio-Mimicking Catalysts for Atom Transfer Radical Polymerization

Molecules ◽  
2019 ◽  
Vol 24 (21) ◽  
pp. 3969 ◽  
Author(s):  
Liye Fu ◽  
Antonina Simakova ◽  
Sangwoo Park ◽  
Yi Wang ◽  
Marco Fantin ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Atom Transfer Radical Polymerization ◽  
Radical Polymerization ◽  
Protein Structures ◽  
Metal Catalyst ◽  
Iron Porphyrin ◽  
Atom Transfer ◽  
Natural Protein ◽  
Naturally Occurring ◽  
Low Toxicity

Copper is the most common metal catalyst used in atom transfer radical polymerization (ATRP), but iron is an excellent alternative due to its natural abundance and low toxicity compared to copper. In this work, two new iron-porphyrin-based catalysts inspired by naturally occurring proteins, such as horseradish peroxidase, hemoglobin, and cytochrome P450, were synthesized and tested for ATRP. Natural protein structures were mimicked by attaching imidazole or thioether groups to the porphyrin, leading to increased rates of polymerization, as well as providing polymers with low dispersity, even in the presence of ppm amounts of catalysts.

Redox Responsive Behavior of Thiol/Disulfide-Functionalized Star Polymers Synthesized via Atom Transfer Radical Polymerization

2010 ◽  
Vol 43 (9) ◽  
pp. 4133-4139 ◽  
Author(s):  
Jun Kamada ◽  
Kaloian Koynov ◽  
Cathrin Corten ◽  
Azhar Juhari ◽  
Jeong Ae Yoon ◽  
...  
Keyword(s):  
Atom Transfer Radical Polymerization ◽  
Radical Polymerization ◽  
Star Polymers ◽  
Atom Transfer ◽  
Redox Responsive ◽  
Responsive Behavior
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