Switchable 19F MRI polymer theranostics: towards in situ quantifiable drug release

2017 ◽  
Vol 8 (34) ◽  
pp. 5157-5166 ◽  
Author(s):  
A. V. Fuchs ◽  
A. P. Bapat ◽  
G. J. Cowin ◽  
K. J. Thurecht

A switchable polymeric 19F magnetic resonance imaging (MRI) contrast agent was synthesised whereby the transverse (T2) relaxation times increased as a therapeutic was released from a hyperbranched polymer (HBP) scaffold.

RSC Advances ◽  
2020 ◽  
Vol 10 (23) ◽  
pp. 13872-13878 ◽  
Author(s):  
Yining Yan ◽  
Lei Ding ◽  
Lin Liu ◽  
Murad M. A. Abualrejal ◽  
Hongda Chen ◽  
...  

Hyaluronic acid functionalized NaGdF4 nanodots were synthesized and evaluated as an active tumor-targeting magnetic resonance imaging (MRI) contrast agent.


Nanoscale ◽  
2015 ◽  
Vol 7 (20) ◽  
pp. 9174-9184 ◽  
Author(s):  
Jeotikanta Mohapatra ◽  
Arijit Mitra ◽  
Himanshu Tyagi ◽  
D. Bahadur ◽  
M. Aslam

An efficient magnetic resonance imaging (MRI) contrast agent with a highR2relaxivity value is achieved by controlling the shape of iron oxide to rod like morphology with a length of 30–70 nm and diameter of 4–12 nm.


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