Microwave-responsive polymeric core–shell microcarriers for high-efficiency controlled drug release

2017 ◽  
Vol 5 (19) ◽  
pp. 3541-3549 ◽  
Author(s):  
Ye Shi ◽  
Chongbo Ma ◽  
Yan Du ◽  
Guihua Yu

A general drug carrier with a unique conjugated polymer/PNIPAM core–shell structure is synthesized for high-efficiency controlled drug release under microwave irradiation.

NANO ◽  
2014 ◽  
Vol 09 (04) ◽  
pp. 1450042 ◽  
Author(s):  
CONG-WANG ZHANG ◽  
CHANG-CHUN ZENG ◽  
YING XU

Fe 3 O 4– SiO 2 core–shell structure nanoparticles containing magnetic properties were investigated for their potential use in drug delivery. The Fe 3 O 4– SiO 2 core–shell structure nanoparticles were successfully synthesized by a simple and convenient way. The Fe 3 O 4– SiO 2 nanoparticles showed superparamagnetic behavior, indicating a great application potential in separation technologies. From the application point of view, the prepared nanoparticles were found to act as an efficient drug carrier. Specifically, the surface of the core–shell nanoparticles was modified with amino groups by use of silane coupling agent 3-aminopropyltriethoxysilane (APTS). Doxorubicin (DOX) was successfully grafted to the surface of the core–shell nanoparticles after the decoration with the carboxyl acid groups on the surface of amino-modified core–shell structure nanoparticles. Moreover, the nanocomposite showed a good drug delivery performance in the DOX-loading efficiency and drug release experiments, confirming that the materials had a great application potential in drug delivery. It is envisioned that the prepared materials are the ideal agent for application in medical diagnosis and therapy.


2014 ◽  
Vol 35 (18) ◽  
pp. NA-NA
Author(s):  
Chih-Hui Yang ◽  
Chih-Yu Wang ◽  
Alexandru Mihai Grumezescu ◽  
Andrew H.-J. Wang ◽  
Ching-Ju Hsiao ◽  
...  

2015 ◽  
Vol 54 (25) ◽  
pp. 7376-7380 ◽  
Author(s):  
Chongbo Ma ◽  
Ye Shi ◽  
Danilo A. Pena ◽  
Lele Peng ◽  
Guihua Yu

2014 ◽  
Vol 35 (18) ◽  
pp. 2673-2680 ◽  
Author(s):  
Chih-Hui Yang ◽  
Chih-Yu Wang ◽  
Alexandru Mihai Grumezescu ◽  
Andrew H.-J. Wang ◽  
Ching-Ju Hsiao ◽  
...  

2016 ◽  
Vol 4 (23) ◽  
pp. 4156-4163 ◽  
Author(s):  
Jianmin Yang ◽  
Daisuke Katagiri ◽  
Sifeng Mao ◽  
Hulie Zeng ◽  
Hizuru Nakajima ◽  
...  

A thermoresponsive polymer microcapsule with a hollow core–porous shell structure was fabricated based on inkjet printing, which can be used to control drug release by changing the temperature at around 38 °C.


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