Sequential controlled-released dual-drug loaded scaffold for guided bone regeneration in a rat fenestration defect model

A 3D multifunctional scaffold, which combines the merits of osseous regeneration and local anti-inflammatory drug delivery, has been developed for GBR.

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The Release of the Bromodomain Ligand N,N-Dimethylacetamide Adds Bioactivity to a Resorbable Guided Bone Regeneration Membrane in a Rabbit Calvarial Defect Model

Materials ◽

10.3390/ma13030501 ◽

2020 ◽

Vol 13 (3) ◽

pp. 501 ◽

Cited By ~ 1

Author(s):

Barbara Siegenthaler ◽

Chafik Ghayor ◽

Nisarat Ruangsawasdi ◽

Franz E. Weber

Keyword(s):

Drug Delivery ◽

Bone Regeneration ◽

Guided Bone Regeneration ◽

Good Combination ◽

Calvarial Defect ◽

Delivery Vehicle ◽

Defect Model ◽

Therapeutic Benefits ◽

Biodegradable Poly

N,N-Dimethylacetamide (DMA) is FDA approved as an excipient and is used as drug-delivery vehicle. Due to its amphipathic nature and diverse bioactivities, it appears to be a good combination of biodegradable poly-lactide-co-glycolide (PLGA)-based guided bone regeneration membranes. Here we show that the solvent DMA can be loaded to PLGA membranes by different regimes, leading to distinct release profiles, and enhancing the bone regeneration in vivo. Our results highlight the potential therapeutic benefits of DMA in guided bone regeneration procedures, in combination with biodegradable PLGA membranes.

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Natural rubber latex used as drug delivery system in guided bone regeneration (GBR)

Materials Research ◽

10.1590/s1516-14392009000200023 ◽

2009 ◽

Vol 12 (2) ◽

pp. 253-256 ◽

Cited By ~ 60

Author(s):

Rondinelli Donizetti Herculano ◽

Cecília Pereira Silva ◽

Cibele Ereno ◽

Sérgio Augusto Catanzaro Guimaraes ◽

Angela Kinoshita ◽

...

Keyword(s):

Drug Delivery ◽

Natural Rubber ◽

Bone Regeneration ◽

Drug Delivery System ◽

Delivery System ◽

Natural Rubber Latex ◽

Guided Bone Regeneration ◽

Rubber Latex

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Company News

Asia-Pacific Biotech News ◽

10.1142/s0219030303001010 ◽

2003 ◽

Vol 07 (10) ◽

pp. 496-502

Keyword(s):

Drug Delivery ◽

Japanese Firm ◽

Inflammatory Drug ◽

Synthetic Dna ◽

Business News ◽

Medical Standard ◽

Anti Inflammatory ◽

Delivery Technology

Prima Subsidiary Breakthrough in Malaria Experiments. Biota Achieves HIV Drug Breakthrough. China Business News. Sino-French Collaboration. US to Export Synthetic DNA to Japanese Firm. Genesis and EvoGenix Collaborates to Discover Anti-Inflammatory Drug. Biomedical Strategy Consultants Marches into Europe. Athelas and MerLion to Work Together on Anti-Infectives. BioPhotoFullerenes to Open HQ in Taiwan. Kiotek to Produce Medical-Standard Chitosan. TaiGen to Buy Microbubble Drug Delivery Technology. Intel Launches Itanium2 Server to Address Bioinformatics Market.

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Synthesis and characterization of zinc adeninate metal-organic frameworks (bioMOF1) as potential anti-inflammatory drug delivery material

10.1063/1.5034549 ◽

2018 ◽

Cited By ~ 1

Author(s):

Ken Aldren S. Usman ◽

Salvador C. Buenviaje ◽

Joselito M. Razal ◽

Marlon T. Conato ◽

Leon M. Payawan

Keyword(s):

Drug Delivery ◽

Metal Organic Frameworks ◽

Synthesis And Characterization ◽

Inflammatory Drug ◽

Metal Organic ◽

Anti Inflammatory

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Stimuli Responsive Scaffolds Based on Carboxymethyl Starch and Poly(2‐Dimethylaminoethyl Methacrylate) for Anti‐Inflammatory Drug Delivery

Macromolecular Bioscience ◽

10.1002/mabi.201900412 ◽

2020 ◽

Vol 20 (4) ◽

pp. 1900412 ◽

Cited By ~ 2

Author(s):

Loredana Elena Nita ◽

Aurica P. Chiriac ◽

Alina Gabriela Rusu ◽

Alina Ghilan ◽

Raluca P. Dumitriu ◽

...

Keyword(s):

Drug Delivery ◽

Stimuli Responsive ◽

Inflammatory Drug ◽

Carboxymethyl Starch ◽

Dimethylaminoethyl Methacrylate ◽

Anti Inflammatory

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A drug delivery system based on switchable photo-controlled p-coumaric acid derivatives anchored on mesoporous silica

Journal of Materials Chemistry B ◽

10.1039/c6tb02040b ◽

2017 ◽

Vol 5 (4) ◽

pp. 817-825 ◽

Cited By ~ 23

Author(s):

Eva Beňová ◽

Vladimír Zeleňák ◽

Dáša Halamová ◽

Miroslav Almáši ◽

Veronika Petrul'ová ◽

...

Keyword(s):

Drug Delivery ◽

Mesoporous Silica ◽

Drug Delivery System ◽

Delivery System ◽

Coumaric Acid ◽

Inflammatory Drug ◽

Anti Inflammatory

Mesoporous silica modified by p-coumaric acid derivatives as photo-switchable ligands was studied for the delivery of a non-steroidal anti-inflammatory drug.

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