Dextranated poly(urethane amine)s designed for systemic gene delivery in ovarian cancer therapy

2017 ◽  
Vol 5 (30) ◽  
pp. 6119-6127 ◽  
Author(s):  
Jie Zhao ◽  
Fei Han ◽  
Peng Zhao ◽  
Xuejun Wen ◽  
Chao Lin
Keyword(s):  
Ovarian Cancer ◽  
Gene Therapy ◽  
Cancer Therapy ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Cancer Gene ◽  
Systemic Gene Delivery

Dextranated poly(urethane amine)s can be designed for robust ovarian cancer gene therapy.

scholarly journals Transcriptional Targeting in Cancer Gene Therapy

2003 ◽  
Vol 2003 (2) ◽  
pp. 110-137 ◽  
Author(s):  
Tracy Robson ◽  
David G. Hirst
Keyword(s):  
Gene Therapy ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Cancer Gene ◽  
Cancer Treatments ◽  
Transcriptional Targeting ◽  
Exogenous Agents ◽  
Therapeutic Research ◽  
Systemic Gene Delivery ◽  
Near Future

Cancer gene therapy has been one of the most exciting areas of therapeutic research in the past decade. In this review, we discuss strategies to restrict transcription of transgenes to tumour cells. A range of promoters which are tissue-specific, tumour-specific, or inducible by exogenous agents are presented. Transcriptional targeting should prevent normal tissue toxicities associated with other cancer treatments, such as radiation and chemotherapy. In addition, the specificity of these strategies should provide improved targeting of metastatic tumours following systemic gene delivery. Rapid progress in the ability to specifically control transgenes will allow systemic gene delivery for cancer therapy to become a real possibility in the near future.

scholarly journals Light-induced adenovirus gene transfer, an efficient and specific gene delivery technology for cancer gene therapy

2002 ◽  
Vol 9 (4) ◽  
pp. 365-371 ◽  
Author(s):  
Anders Høgset ◽  
Birgit Øvstebø Engesæter ◽  
Lina Prasmickaite ◽  
Kristian Berg ◽  
Øystein Fodstad ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Gene Transfer ◽  
Gene Delivery ◽  
Cancer Gene Therapy ◽  
Specific Gene ◽  
Cancer Gene ◽  
Delivery Technology

scholarly journals Fluorescent Imaging for Cancer Therapy and Cancer Gene Therapy

2021 ◽  
Author(s):  
Yanghee Woo ◽  
Shyambabu Chaurasiya ◽  
Michael O’Leary ◽  
Ernest Han ◽  
Yuman Fong
Keyword(s):  
Gene Therapy ◽  
Cancer Therapy ◽  
Cancer Gene Therapy ◽  
Fluorescent Imaging ◽  
Cancer Gene

Transcriptional Targeting for Ovarian Cancer Gene Therapy

2001 ◽  
Vol 82 (2) ◽  
pp. 229-237 ◽  
Author(s):  
E. Casado ◽  
D.M. Nettelbeck ◽  
J. Gomez-Navarro ◽  
A. Hemminki ◽  
M. Gonzalez Baron ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Gene Therapy ◽  
Cancer Gene Therapy ◽  
Cancer Gene ◽  
Transcriptional Targeting

In Vivo Ovarian Cancer Gene Therapy Using CRISPR-Cas9

2018 ◽  
Vol 29 (2) ◽  
pp. 223-233 ◽  
Author(s):  
Zhi-Yao He ◽  
Ya-Guang Zhang ◽  
Yu-Han Yang ◽  
Cui-Cui Ma ◽  
Ping Wang ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Gene Therapy ◽  
Cancer Gene Therapy ◽  
Cancer Gene

scholarly journals Preclinical evaluation of a class of infectivity-enhanced adenoviral vectors in ovarian cancer gene therapy

Gene Therapy ◽  
2004 ◽  
Vol 11 (10) ◽  
pp. 874-878 ◽  
Author(s):  
H Wu ◽  
T Han ◽  
J T Lam ◽  
C A Leath ◽  
I Dmitriev ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Gene Therapy ◽  
Cancer Gene Therapy ◽  
Adenoviral Vectors ◽  
Cancer Gene ◽  
Preclinical Evaluation
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