Identification of proteins and bacteria based on a metal ion–gold nanocluster sensor array

2018 ◽  
Vol 10 (32) ◽  
pp. 3939-3944 ◽  
Author(s):  
Yayan Wu ◽  
Bing Wang ◽  
Kai Wang ◽  
Peng Yan

We report a simple fluorescence sensor array based on metal ions–gold nanoclusters (AuNCs) for the identification of proteins. The proposed method can also be used for bacteria sensing.

2022 ◽  
Author(s):  
Zijun Xu ◽  
Yuying Liu ◽  
Jiao Chen ◽  
Xiyuan Wang ◽  
Hao Liu ◽  
...  

Abstract As a large amount of heavy metals leaches into water sources from industrial effluents, heavy metal pollution has become an important factor affecting water quality. To enable the detection of multiple heavy metals, we constructed a pH-regulation fluorescence sensor array. Firstly, by adding a metal chelating agent as receptor, metal ions and carbon quantum dots (CDs) were connected to distinguish between Cr6+, Fe3+, Fe2+, and Hg2+ ions. Thus, the lack of affinity between the indicator functional groups and the analyte was solved. Secondly, by adjusting the pH environment of the solution system, an economical and simple array sensing platform is established, which effectively simplified the array construction. In this study, the SX-model was used in the field of fluorescence sensor array detection for metal ion recognition. Based on the strategy of stepwise prediction, combined with the classification and concentration models, the bottleneck of the unified model in previous studies was broken. This sensor array demonstrated sensitive detection of four heavy metal ions within a concentration range from 1 to 50 µM, with an accuracy of 95.45%. Moreover, it displayed the ability to efficiently identify binary mixed samples with an accuracy of 95.45%. Furthermore, metal ions in 15 real samples (lake water) were effectively discriminated with 100% accuracy. A chelating agent was used to improve the sensitivity of heavy metal ion detection and eventually led to high-precision prediction using the SX-model.


2019 ◽  
Vol 11 (1) ◽  
pp. 17-20 ◽  
Author(s):  
Li Li ◽  
Bing Liu ◽  
Zhengbo Chen

In this work, we developed a facile and extensible colorimetric sensor array based on different interactions between methylene blue (MB) and single-stranded DNA (ssDNA) for the discrimination of heavy metal ions.


2020 ◽  
pp. 124259
Author(s):  
Xiang-Ping Zhang ◽  
Kai-Yuan Huang ◽  
Shao-Bin He ◽  
Hua-Ping Peng ◽  
Xing-Hua Xia ◽  
...  

2019 ◽  
Vol 11 (41) ◽  
pp. 5274-5281 ◽  
Author(s):  
Jiawei Li ◽  
Ping Yang ◽  
Jing Zhang ◽  
Zhengfan Shui ◽  
Danqun Huo ◽  
...  

We provide a Baijiu colorimetric sensor array based on metal ions regulated Au NPs aggregation, which can do a correct classification of 16 Baijius with different flavor types.


2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Yan Qiu ◽  
Jianlin Huang ◽  
Li Jia

A fluorescence sensor for the detection of glutathione based on the fluorescence recovering of the bovine serum albumin-stabilized gold nanoclusters is reported. This study indicates that glutathione restores the copper-ion-quenched fluorescence by coordinating the bound copper ion in the bovine serum albumin molecule used for stabilizing the gold nanocluster through its sulfydryl. Under the experimental conditions, the fluorescence response showed a linear relationship with the concentration of glutathione over the range from 10 µM to 400 µM. The fluorescence sensor successfully detected glutathione in commercial drug products.


2019 ◽  
Vol 11 (25) ◽  
pp. 3168-3174 ◽  
Author(s):  
Jiao Li ◽  
Hui Huang ◽  
Xue Sun ◽  
Donghui Song ◽  
Jingqi Zhao ◽  
...  

An efficient method has been found to discriminate different brands of packaged water which achieves to detect counterfeit products in the packaged water market.


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