The intervention effect of licorice in d-galactose induced aging rats by regulating the taurine metabolic pathway

It is well known that epithelial hyperplasia (benign hypertrophy) is common in the aging prostate of dogs and man. In contrast, little evidence is available for abnormal epithelial cell growth in seminal vesicles of aging animals. Recently, enlarged seminal vesicles were reported in senescent mice, however, that enlargement resulted from increased storage of secretion in the lumen and occurred concomitant to epithelial hypoplasia in that species.The present study is concerned with electron microscopic observations of changes occurring in the pseudostratified epithelium of the seminal vescles of aging rats. Special attention is given to certain non-epithelial cells which have entered the epithelial layer.

Download Full-text

Simultaneous HPLC determination of four key metabolites in the metabolic pathway for production of 1,3-propanediol from glycerol

Chromatographia ◽

10.1016/s0009-5893(07)82072-8 ◽

2007 ◽

Vol 65 (9-10) ◽

pp. 629-632

Author(s):

H CHEN ◽

B FANG ◽

Z HU

Keyword(s):

Metabolic Pathway ◽

Hplc Determination

Download Full-text

Does CBT for Psychosis Have an Impact on Delusions by Improving Reasoning Biases and Negative Self-Schemas?

Zeitschrift für Psychologie ◽

10.1027/2151-2604/a000335 ◽

2018 ◽

Vol 226 (3) ◽

pp. 152-163 ◽

Cited By ~ 2

Author(s):

Stephanie Mehl ◽

Björn Schlier ◽

Tania M. Lincoln

Keyword(s):

Behavioral Therapy ◽

Theoretical Models ◽

Self Esteem ◽

Secondary Outcome ◽

Intervention Effect ◽

Produce Change ◽

Attribution Biases ◽

Carry Over ◽

Implicit And Explicit ◽

Reasoning Biases

Abstract. Cognitive-behavioral therapy for psychosis (CBTp) builds on theoretical models that postulate reasoning biases and negative self-schemas to be involved in the formation and maintenance of delusions. However, it is unclear whether CBTp induces change in delusions by improving these proposed causal mechanisms. This study reports on a mediation analysis of a CBTp effectiveness trial in which delusions were a secondary outcome. Patients with psychosis were randomized to individualized CBTp (n = 36) or a waiting list condition (WL; n = 34). Reasoning biases (jumping to conclusions, theory of mind, attribution biases) and self-schemas (implicit and explicit self-esteem; self-schemas related to different domains) were assessed pre- and post-therapy/WL. The results reveal an intervention effect on two of four measures of delusions and on implicit self-esteem. Nevertheless, the intervention effect on delusions was not mediated by implicit self-esteem. Changes in explicit self-schemas and reasoning biases did also not mediate the intervention effects on delusions. More focused interventions may be required to produce change in reasoning and self-schemas that have the potential to carry over to delusions.

Download Full-text

Glucose regulation of secretory and metabolic pathway genes in human pancreatic islets

Experimental and Clinical Endocrinology & Diabetes ◽

10.1055/s-2005-862882 ◽

2005 ◽

Vol 113 (S 1) ◽

Author(s):

BJ Manfras ◽

P Hengster ◽

BO Böhm

Keyword(s):

Pancreatic Islets ◽

Metabolic Pathway ◽

Glucose Regulation ◽

Human Pancreatic Islets

Download Full-text

Genipin, the UCP2 Inhibitor, Depresses Heart Function of Aging Rats

International Journal of Physiology and Pathophysiology ◽

10.1615/intjphyspathophys.v1.i2.10 ◽

2010 ◽

Vol 1 (2) ◽

pp. 95-101

Author(s):

Yulia V. Goshovska ◽

Tatiana V. Shimanskaya ◽

Vadym F. Sagach

Keyword(s):

Heart Function ◽

Aging Rats

Download Full-text

PERLAKUAN ETHYL METHANE SULFONATE (EMS) PADA ENTEROBACTER AEROGENES AY-2 DARI LIMBAH METAN FERMENTASI UNTUK PENINGKATAN PRODUKSI GAS HIDROGEN

Jurnal Rekayasa Lingkungan ◽

10.29122/jrl.v5i1.1875 ◽

2018 ◽

Vol 5 (1) ◽

Author(s):

Mahyudin Abdul Rachman

Keyword(s):

Metabolic Pathway ◽

Acid Production ◽

Double Mutant ◽

Enterobacter Aerogenes ◽

H2 Production ◽

Hydrogen Gas ◽

Survival Ratio ◽

Ethyl Methane Sulfonate ◽

Methane Sulfonate ◽

Ethyl Methane

Enterobacter aerogenes AY-2 mutant is known for hydrogen gas producer which ws obtained from the sludge of methane fermentation and the yield is 1.5 fold higher than wildtype. Hydrogen gas production can be gain via NADH oxidation in anaerobic metabolic pathway by blocking organic acid production. Metabolic pathway can be changed by mutagenesis. Enterobacter aerogenes AY-2 mutated with ethyl methane sulfonate in logarithmic phase with consentration 10, 11, 12, 13, 14 and 15 μl/ml cell suspention during 120 minute. Mutation that result lowest survival ratio (0,01%) was 14 μl EMS/ml cell suspention is repeated with variation incubation time, 30, 60, 90 and 120 minute. 166 double mutant colony has been collected and choosen randomly. The choosen 43 colony was fermented in glycerol complex medium for determining ten double mutant with the highest H2 production. Double mutant AD-H43 is a highest H2 producer that increase 20% H2 production from AY-2 and has a decrease lactid acid production, 31% less from AY-2. Increasing H2 production in double mutant AD-H43 is caused by lactate dehydrogenase deffi cient.Keywords: Enterobacter aerogenes AY-2, ethyl methane sulfonate (EMS), H2 and methane sludge

Download Full-text