Brosimone I, an isoprenoid-substituted flavonoid, induces cell cycle G1phase arrest and apoptosis through ROS-dependent endoplasmic reticulum stress in HCT116 human colon cancer cells

Brosimone I, an isoprenoid-substituted flavonoid fromArtocarpus heterophyllus, induces cell growth inhibition through the induction of ROS-mediated increased cytosolic Ca2+, ER stress, and the activation of the CaMKK-AMPK pathway.