scholarly journals Synthesis, biological evaluation, and structure activity relationship (SAR) study of pyrrolidine amide derivatives as N-acylethanolamine acid amidase (NAAA) inhibitors

MedChemComm ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 252-262 ◽  
Author(s):  
Pan Zhou ◽  
Lei Xiang ◽  
Dongsheng Zhao ◽  
Jie Ren ◽  
Yan Qiu ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Structure Activity Relationship ◽  
Biological Evaluation ◽  
Activity Relationship ◽  
Key Enzymes ◽  
Structure Activity ◽  
Amide Derivatives ◽  
Fatty Acid Ethanolamides ◽  
Sar Study

N-Acylethanolamine acid amidase (NAAA) is one of the key enzymes involved in the degradation of fatty acid ethanolamides (FAEs), especially for palmitoylethanolamide (PEA).

Structure Activity Relationship of Arylidene Pyrrolo and Pyrido [2,1-b] Quinazolones as Cytotoxic Agents: Synthesis, SAR Studies, Biological Evaluation and Docking Studies

2013 ◽  
Vol 9 (5) ◽  
pp. 642-650 ◽  
Author(s):  
Veenu Mangla ◽  
Kunal Nepali ◽  
Gagandip Singh ◽  
Jagjeet Singh ◽  
Santosh Guru ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Cytotoxic Agents ◽  
Activity Relationship ◽  
Sar Studies ◽  
Structure Activity ◽  
Relationship Of

An Organocatalysis Based Carbocyclic Spiroindoline Synthesis Enables Facile Structure–Activity Relationship (SAR) Study at C2 Position

2015 ◽  
Vol 17 (17) ◽  
pp. 4240-4243 ◽  
Author(s):  
Yongsheng Zheng ◽  
Jacob Cleaveland ◽  
David Richardson ◽  
Yu Yuan
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Sar Study
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