scholarly journals A fluorescent methylation-switchable probe for highly sensitive analysis of FTO N6-methyladenosine demethylase activity in cells

2018 ◽  
Vol 9 (36) ◽  
pp. 7174-7185 ◽  
Author(s):  
Adeline Cheong ◽  
Joanne J. A. Low ◽  
Andrea Lim ◽  
Paul M. Yen ◽  
Esther C. Y. Woon
Keyword(s):  
Methylation Status ◽  
Sensitive Detection ◽  
Sensitive Analysis ◽  
Highly Sensitive ◽  
Demethylase Activity ◽  
Highly Sensitive Detection ◽  
In Cells

A dynamic biosensor which switches conformation according to its methylation status enables highly sensitive detection of m6A-demethylase activity. This strategy may be adapted to a broad range of RNA-modifying enzymes.

scholarly journals Oriented Conjugates of Single-domain Antibodies and Fluorescent Quantum Dots for Highly Sensitive Detection of Tumor-associated Biomarkers in Cells and Tissues

2015 ◽  
Vol 73 ◽  
pp. 228-234 ◽  
Author(s):  
Regina Bilan ◽  
Kristina Brazhnik ◽  
Patrick Chames ◽  
Daniel Baty ◽  
Igor Nabiev ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Single Domain ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Single Domain Antibodies ◽  
Highly Sensitive Detection ◽  
In Cells

Lanthanide Coordination Polymer-Based Composite Films for Selective and Highly Sensitive Detection of Cr2O72– in Aqueous Media

2019 ◽  
Vol 58 (22) ◽  
pp. 15118-15125 ◽  
Author(s):  
Wei Chen ◽  
Ruiqing Fan ◽  
Jizhuang Fan ◽  
Haiyu Liu ◽  
Tiancheng Sun ◽  
...  
Keyword(s):  
Coordination Polymer ◽  
Aqueous Media ◽  
Composite Films ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Lanthanide Coordination Polymer ◽  
Highly Sensitive Detection

Highly Sensitive Detection of Paraquat with Pillar[5]arene as an aptamer in α-Hemolysin Nanopore

2021 ◽  
Author(s):  
Xiaojia Jiang ◽  
Mingsong Zang ◽  
Fei Li ◽  
Chunxi Hou ◽  
Quan Luo ◽  
...  
Keyword(s):  
Real Time ◽  
High Throughput ◽  
Single Molecule ◽  
Single Molecule Detection ◽  
Sensitive Detection ◽  
High Throughput Analysis ◽  
Throughput Analysis ◽  
The Real ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

Biological nanopore-based techniques have attracted more and more attention recently in the field of single-molecule detection, because they allow the real-time, sensitive, high-throughput analysis. Herein, we report an engineered biological...

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