Facile fabrication of thermo/redox responsive hydrogels based on a dual crosslinked matrix for a smart on–off switch

Soft Matter ◽  
2018 ◽  
Vol 14 (21) ◽  
pp. 4327-4334 ◽  
Author(s):  
Na Sun ◽  
Panpan Sun ◽  
Aoli Wu ◽  
Xuanxuan Qiao ◽  
Fei Lu ◽  
...  
Keyword(s):  
Chemical Crosslinking ◽  
Redox Responsive ◽  
Facile Fabrication ◽  
Responsive Hydrogels ◽  
Physical Crosslinking ◽  
Polyelectrolyte Hydrogel

A thermo- and redox-responsive polyelectrolyte hydrogel was facilely constructed based on a primary chemical crosslinking and a secondary physical crosslinking.

scholarly journals Stereocomplexation of Poly(lactic acid) and Chemical Crosslinking of Ethylene Glycol Dimethacrylate (EGDMA) Double-Crosslinked Temperature/pH Dual Responsive Hydrogels

Polymers ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 2204
Author(s):  
Zhidan Wang ◽  
Jie Wu ◽  
Xiaoyu Shi ◽  
Fei Song ◽  
Wenli Gao ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Ethylene Glycol ◽  
Crosslinking Agent ◽  
Ethylene Glycol Dimethacrylate ◽  
Poly Lactic Acid ◽  
Chemical Crosslinking ◽  
Glycol Dimethacrylate ◽  
Dual Responsive ◽  
Responsive Hydrogels ◽  
Physical Crosslinking

Physical crosslinking and chemical crosslinking were used to further improve the mechanical properties and stability of the gel. A temperature/pH dual sensitive and double-crosslinked gel was prepared by the stereo-complex of HEMA-PLLA20 and HEMA-PDLA20 as a physical crosslinking agent, ethylene glycol dimethacrylate (EGDMA) as a chemical crosslinking agent, and azodiisobutyronitrile (AIBN) as an initiator for free radical polymerization. This paper focused on the performance comparison of chemical crosslinked gel, a physical crosslinked gel, and a dual crosslinked gel. The water absorption, temperature, and pH sensitivity of the three hydrogels were studied by a scanning electron microscope (SEM) and swelling performance research. We used a thermal analysis system (TGA) and dynamic viscoelastic spectrometer to study thermal properties and mechanical properties of these gels. Lastly, the in vitro drug release behavior of double-crosslinked hydrogel loaded with doxorubicin under different conditions was studied. The results show that the double-crosslinked and temperature/pH dual responsive hydrogels has great mechanical properties and good stability.

Metal Nanoparticle Foundry with Redox Responsive Hydrogels

2018 ◽  
Vol 219 (22) ◽  
pp. 1800223 ◽  
Author(s):  
Xueling Feng ◽  
Mark A. Hempenius ◽  
Gyula J. Vancso
Keyword(s):  
Metal Nanoparticle ◽  
Redox Responsive ◽  
Responsive Hydrogels

Double‐crosslinked reversible redox‐responsive hydrogels based on disulfide–thiol interchange

2019 ◽  
Vol 57 (24) ◽  
pp. 2590-2601 ◽  
Author(s):  
Yunjiao Che ◽  
Stefan Zschoche ◽  
Franziska Obst ◽  
Dietmar Appelhans ◽  
Brigitte Voit
Keyword(s):  
Reversible Redox ◽  
Redox Responsive ◽  
Responsive Hydrogels

Best of both worlds: Diels–Alder chemistry towards fabrication of redox-responsive degradable hydrogels for protein release

RSC Advances ◽  
2016 ◽  
Vol 6 (78) ◽  
pp. 74757-74764 ◽  
Author(s):  
Ismail Altinbasak ◽  
Rana Sanyal ◽  
Amitav Sanyal
Keyword(s):  
Ethylene Glycol ◽  
Alder Reaction ◽  
Diels Alder ◽  
Protein Release ◽  
Poly Ethylene Glycol ◽  
Diels Alder Reaction ◽  
Redox Responsive ◽  
Poly Ethylene ◽  
Responsive Hydrogels

Poly(ethylene glycol)-based redox-responsive hydrogels have been preparedviathe Diels–Alder reaction between a furan-containing hydrophilic copolymer and a disulfide-containing bis-maleimide based crosslinker.

Redox-responsive hydrogels

2017 ◽  
pp. 31-60 ◽  
Author(s):  
Weiren Cheng ◽  
Ye Liu
Keyword(s):  
Redox Responsive ◽  
Responsive Hydrogels

Temperature and Redox‐Responsive Hydrogels Based on Nitroxide Radicals and Oligoethyleneglycol Methacrylate

2020 ◽  
Vol 221 (6) ◽  
pp. 1900550
Author(s):  
Miriam Khodeir ◽  
Sayed Antoun ◽  
Evelyne Ruymbeke ◽  
Jean‐François Gohy
Keyword(s):  
Nitroxide Radicals ◽  
Redox Responsive ◽  
Responsive Hydrogels

scholarly journals Poly(vinyl alcohol): Physical Approaches to Designing Biomaterials for Biomedical Applications

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Shathani Nkhwa ◽  
Kristo Fernando Lauriaga ◽  
Evren Kemal ◽  
Sanjukta Deb
Keyword(s):  
Vinyl Alcohol ◽  
Biomedical Applications ◽  
Physical And Mechanical Properties ◽  
Poly Vinyl Alcohol ◽  
Biocompatible Polymers ◽  
Chemical Crosslinking ◽  
Biocompatible Polymer ◽  
Physical Methods ◽  
Physically Crosslinked ◽  
Physical Crosslinking

Poly(vinyl alcohol) is a non-toxic, biosynthetic polymer and biocompatible polymer that has the ability to form hydrogels either via chemical or physical crosslinking. Whilst chemical crosslinking provides greater control on the properties of the resultant hydrogel, physically crosslinked hydrogels or blends with other biocompatible polymers are more suited for biomedical applications. In this paper we report a systematic study on the effect of varying concentrations of PVA, physical methods of crosslinking, and PVA-gelatin and PVA-PVP blends on the physical and mechanical properties of the hydrogels.

Enzymatically prepared redox-responsive hydrogels as potent matrices for hepatocellular carcinoma cell spheroid formation

2016 ◽  
Vol 11 (11) ◽  
pp. 1452-1460 ◽  
Author(s):  
Kousuke Moriyama ◽  
Shono Naito ◽  
Rie Wakabayashi ◽  
Masahiro Goto ◽  
Noriho Kamiya
Keyword(s):  
Hepatocellular Carcinoma ◽  
Carcinoma Cell ◽  
Spheroid Formation ◽  
Cell Spheroid ◽  
Redox Responsive ◽  
Hepatocellular Carcinoma Cell ◽  
Responsive Hydrogels

Study on the Crosslinkers Used in Gelling Agents

2014 ◽  
Vol 936 ◽  
pp. 1549-1552
Author(s):  
Qian Ru Sun ◽  
Rong Wei Liu
Keyword(s):  
Polymer Chains ◽  
Chemical Crosslinking ◽  
Gelling Agents ◽  
Physical Crosslinking

This paper is closely related to the crosslinkers used in gelling agents. Both physical crosslinking and chemical crosslinking are discussed. Crosslinkers are added to form intermolecular linkages in between the primary polymer chains to form a stable gel. Both gelling and plugging agents have similar aims---to minimize the permeability of a formation. With the producing water is becoming the big problem, crosslinkers are becoming more important.

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