Carboplatin-loaded SMNDs to reduce GSH-mediated platinum resistance for prostate cancer therapy

2018 ◽  
Vol 6 (43) ◽  
pp. 7004-7014 ◽  
Author(s):  
Shuang Liang ◽  
Leiqiang Han ◽  
Weiwei Mu ◽  
Dandan Jiang ◽  
Teng Hou ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Drug Resistance ◽  
Cancer Therapy ◽  
Platinum Resistance ◽  
Therapeutic Efficiency ◽  
Prostate Cancer Therapy

Glutathione (GSH)-mediated drug resistance can strongly weaken the therapeutic efficiency of platinum(ii).

Nanoparticle Therapy for Prostate Cancer: Overview and Perspectives

2019 ◽  
Vol 19 (1) ◽  
pp. 57-73 ◽  
Author(s):  
Junfu Zhang ◽  
Liying Wang ◽  
Xinru You ◽  
Tuzeng Xian ◽  
Jun Wu ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Drug Resistance ◽  
Cancer Therapy ◽  
Influencing Factors ◽  
Treatment Effects ◽  
Tumor Site ◽  
Chemotherapy Drugs ◽  
Imaging Examination ◽  
Prostate Cancer Therapy ◽  
Rapid Clearance

Traditional prostate cancer therapy and especially chemotherapy has faced many challenges. Low accumulation levels, rapid clearance or drug resistance at the tumor site have been central to why the effect of chemotherapy drugs has declined. Applications of nanotechnology to biomedicine have enabled the development of nanoparticle therapeutic carriers suited for the delivery of chemotherapeutics in cancer therapy. This review describes the current nature of nanoparticle therapeutic carriers for prostate cancer. It describes typical nanocarriers commonly used for the delivery of chemotherapy or for imaging examination. Targeting strategies and related influencing factors are investigated to find ways of enhancing treatment effects of nanoparticles. The overall purpose of this review is to further understanding and to offer recommendations on the design and development of therapeutic nanoparticles for prostate cancer.

Novel Antitumor Strategies Using Cytokine PEDF for Prostate Cancer Therapy

2012 ◽  
Vol 1 (4) ◽  
pp. 277-298 ◽  
Author(s):  
Olga Zolochevska ◽  
Sofia H. Bergstrom ◽  
Brennen Comeaux ◽  
Todd Emrick ◽  
Marxa L. Figueiredo
Keyword(s):  
Prostate Cancer ◽  
Cancer Therapy ◽  
Prostate Cancer Therapy

Synthesis and biological evaluation of seliciclib derivatives as potent and selective CDK9 inhibitors for prostate cancer therapy

2021 ◽  
Vol 152 (1) ◽  
pp. 109-120
Author(s):  
Aisha A. Alsfouk ◽  
Hanan M. Alshibl ◽  
Najla A. Altwaijry ◽  
Bshra A. Alsfouk ◽  
Ebtehal S. Al-Abdullah
Keyword(s):  
Prostate Cancer ◽  
Cancer Therapy ◽  
Biological Evaluation ◽  
Prostate Cancer Therapy ◽  
Synthesis And Biological Evaluation

scholarly journals Plumbagin-loaded aptamer-targeted poly D,L-lactic-co-glycolic acid-b-polyethylene glycol nanoparticles for prostate cancer therapy

Medicine ◽  
2017 ◽  
Vol 96 (30) ◽  
pp. e7405 ◽  
Author(s):  
Minjie Pan ◽  
Weifeng Li ◽  
Jun Yang ◽  
Zhiqin Li ◽  
Jun Zhao ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Polyethylene Glycol ◽  
Cancer Therapy ◽  
Glycolic Acid ◽  
Prostate Cancer Therapy
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