Ultrasensitive detection of the androgen receptor through the recognition of an androgen receptor response element and hybridization chain amplification

The Analyst ◽  
2019 ◽  
Vol 144 (6) ◽  
pp. 2179-2185 ◽  
Author(s):  
Binbin Yao ◽  
Sha Zhu ◽  
Xinyu Xu ◽  
Ninghan Feng ◽  
Yaping Tian ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Restriction Endonuclease ◽  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Dna Duplex ◽  
Chain Reaction ◽  
Response Element ◽  
Receptor Response

The androgen receptor is detected through the protection of a DNA duplex from restriction endonuclease-mediated digestion and a subsequent hybridization chain reaction.

DNA-Based Hybridization Chain Reaction for Amplified Bioelectronic Signal and Ultrasensitive Detection of Proteins

2012 ◽  
Vol 84 (12) ◽  
pp. 5392-5399 ◽  
Author(s):  
Bing Zhang ◽  
Bingqian Liu ◽  
Dianping Tang ◽  
Reinhard Niessner ◽  
Guonan Chen ◽  
...  
Keyword(s):  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Chain Reaction

Target triggered ultrasensitive electrochemical polychlorinated biphenyl aptasensor based on DNA microcapsules and nonlinear hybridization chain reaction

The Analyst ◽  
2020 ◽  
Vol 145 (10) ◽  
pp. 3598-3604 ◽  
Author(s):  
Ting Han ◽  
Shaozhen Wang ◽  
Feifan Sheng ◽  
Sicheng Wang ◽  
Tianyue Dai ◽  
...  
Keyword(s):  
Polychlorinated Biphenyls ◽  
Polychlorinated Biphenyl ◽  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Chain Reaction

In this work, we demonstrated an ultrasensitive detection platform for polychlorinated biphenyls (PCBs) based on DNA microcapsules and a nonlinear hybridization chain reaction (NHCR).

Versatile fluorescence detection of microRNA based on novel DNA hydrogel-amplified signal probes coupled with DNA walker amplification

2019 ◽  
Vol 55 (27) ◽  
pp. 3919-3922 ◽  
Author(s):  
Chunli Li ◽  
Hongkun Li ◽  
Junjun Ge ◽  
Guifen Jie
Keyword(s):  
Fluorescence Detection ◽  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Chain Reaction ◽  
Dna Walker ◽  
Dna Hydrogel

A novel DNA hydrogel-amplified versatile fluorescence platform combined with hybridization chain reaction (HCR) and DNA walking multiple amplification was developed for ultrasensitive detection of miRNA.

MnO2 nanosheet-based heparin and OSCS fluorescent biosensor with lowered background and amplified hybridization chain reaction

RSC Advances ◽  
2016 ◽  
Vol 6 (92) ◽  
pp. 89803-89809 ◽  
Author(s):  
Ruifen Tian ◽  
Hong Jiang ◽  
Guangfeng Wang
Keyword(s):  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Chain Reaction ◽  
Fluorescent Biosensor ◽  
Turn On ◽  
Amplification Strategy ◽  
Mno2 Nanosheet

A “turn-on” ultrasensitive detection of heparin or OSCS was reported through MnO2 nanosheet quenched-ultralow background and HCR amplification strategy.

Phosphorylation-induced hybridization chain reaction on beads: an ultrasensitive flow cytometric assay for the detection of T4 polynucleotide kinase activity

2015 ◽  
Vol 51 (27) ◽  
pp. 5832-5835 ◽  
Author(s):  
Yuecheng Zhang ◽  
Chenghui Liu ◽  
Sujuan Sun ◽  
Yanli Tang ◽  
Zhengping Li
Keyword(s):  
Kinase Activity ◽  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Flow Cytometric Assay ◽  
Chain Reaction ◽  
Flow Cytometric ◽  
Polynucleotide Kinase ◽  
T4 Polynucleotide Kinase

A versatile flow cytometric bead assay (FCBA) has been developed for an ultrasensitive detection of T4 PNK activity.

Dual amplification ratiometric biosensor based on a DNA tetrahedron nanostructure and hybridization chain reaction for the ultrasensitive detection of microRNA-133a

2019 ◽  
Vol 55 (77) ◽  
pp. 11551-11554 ◽  
Author(s):  
Liping Zhu ◽  
Jing Ye ◽  
Shuang Wang ◽  
Mengxia Yan ◽  
Qiuju Zhu ◽  
...  
Keyword(s):  
High Accuracy ◽  
Hybridization Chain Reaction ◽  
Ultrasensitive Detection ◽  
Chain Reaction ◽  
Dna Tetrahedron ◽  
Dual Amplification

A novel ratiometric electrochemiluminescence–electrochemical hybrid biosensor with high accuracy and reproducibility was fabricated for the ultrasensitive detection of miRNA-133a.

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