Ultrasensitive detection of disease biomarkers using an immuno-wall device with enzymatic amplification

The Analyst ◽  
2019 ◽  
Vol 144 (15) ◽  
pp. 4589-4595 ◽  
Author(s):  
Keine Nishiyama ◽  
Toshihiro Kasama ◽  
Seiya Nakamata ◽  
Koya Ishikawa ◽  
Daisuke Onoshima ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Sandwich Immunoassay ◽  
Ultrasensitive Detection ◽  
Disease Biomarkers ◽  
Enzymatic Amplification

We present a fluorometric sandwich immunoassay for biomarkers utilizing an antibody-modified microfabricated wall and antibody labeled with an enzyme for signal amplification.

Ultrasensitive detection of specific IgE based on nanomagnetic capture and separation with AuNP-anti-IgE nanobioprobe for signal amplification

2021 ◽  
Author(s):  
Mengda Cao ◽  
Yongxin Liu ◽  
Chen Lu ◽  
Miao Guo ◽  
Lin Li ◽  
...  
Keyword(s):  
Allergic Disease ◽  
Signal Amplification ◽  
Specific Ige ◽  
Ultrasensitive Detection ◽  
Accurate Detection ◽  
Personalized Diagnosis

The accurate detection of allergen specific IgE (sIgE) is fundamental in the diagnosis of allergic disease. The present commercial platforms fail to meet the need for personalized diagnosis, due to...

A novel label free long non-coding RNA electrochemical biosensor based on green l-cysteine electrodeposition and Au–Rh hollow nanospheres as tags

RSC Advances ◽  
2015 ◽  
Vol 5 (64) ◽  
pp. 51990-51999 ◽  
Author(s):  
Fei Liu ◽  
Guiming Xiang ◽  
Liqun Zhang ◽  
Dongneng Jiang ◽  
Linlin Liu ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Single Wall Carbon Nanotubes ◽  
Complex Signal ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Hollow Nanospheres ◽  
Non Coding Rna ◽  
Long Non Coding Rna

lncRNA biosensor based on single-wall carbon nanotubes wrapped with Au–Rh hollow nanospheres (Au/Rh-HNP@SWCNT) complex signal amplification and an l-Cys Au nano-film provided ultrasensitive detection for the nuclear paraspeckle assembly transcript 1 (NEAT1).

A new enzyme-free quadratic SERS signal amplification approach for circulating microRNA detection in human serum

2015 ◽  
Vol 51 (90) ◽  
pp. 16271-16274 ◽  
Author(s):  
Jing Zheng ◽  
Dandan Ma ◽  
Muling Shi ◽  
Junhui Bai ◽  
Yinhui Li ◽  
...  
Keyword(s):  
Human Serum ◽  
Signal Amplification ◽  
Circulating Microrna ◽  
Ultrasensitive Detection ◽  
Circulating Mirna ◽  
Sers Signal ◽  
Microrna Detection

In this communication, we proposed a new enzyme-free quadratic SERS signal amplification approach for the ultrasensitive detection of circulating miRNA in human serum.

A disposable paper-based electrochemiluminescence device for ultrasensitive monitoring of CEA based on Ru(bpy)32+@Au nanocages

RSC Advances ◽  
2015 ◽  
Vol 5 (36) ◽  
pp. 28324-28331 ◽  
Author(s):  
Chaomin Gao ◽  
Min Su ◽  
Yanhu Wang ◽  
Shenguang Ge ◽  
Jinghua Yu
Keyword(s):  
Signal Amplification ◽  
Ultrasensitive Detection ◽  
Working Electrode

Ultrasensitive detection of CEA based on Ag nanospheres modified paper working electrode platform and Ru(bpy)32+@Au nanocages signal amplification.

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