A novel label free long non-coding RNA electrochemical biosensor based on green l-cysteine electrodeposition and Au–Rh hollow nanospheres as tags

RSC Advances ◽  
2015 ◽  
Vol 5 (64) ◽  
pp. 51990-51999 ◽  
Author(s):  
Fei Liu ◽  
Guiming Xiang ◽  
Liqun Zhang ◽  
Dongneng Jiang ◽  
Linlin Liu ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Single Wall Carbon Nanotubes ◽  
Complex Signal ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Hollow Nanospheres ◽  
Non Coding Rna ◽  
Long Non Coding Rna

lncRNA biosensor based on single-wall carbon nanotubes wrapped with Au–Rh hollow nanospheres (Au/Rh-HNP@SWCNT) complex signal amplification and an l-Cys Au nano-film provided ultrasensitive detection for the nuclear paraspeckle assembly transcript 1 (NEAT1).

scholarly journals Optimization of the Electrodeposition of Gold Nanoparticles for the Application of Highly Sensitive, Label-Free Biosensor

Biosensors ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 50 ◽  
Author(s):  
Hao-Chun Chiang ◽  
Yanyan Wang ◽  
Qi Zhang ◽  
Kalle Levon
Keyword(s):  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Aqueous Electrolyte ◽  
Label Free ◽  
Reduction Step ◽  
Glucose Biosensors ◽  
Highly Sensitive ◽  
Amperometric Glucose Biosensors ◽  
Aunp Surface

A highly sensitive electrochemical biosensor with a signal amplification platform of electrodeposited gold nanoparticle (AuNP) has been developed and characterized. The sizes of the synthesized AuNP were found to be critical for the performance of biosensor in which the sizes were dependent on HAuCl4 and acid concentrations; as well as on scan cycles and scan rates in the gold electro-reduction step. Systematic investigations of the adsorption of proteins with different sizes from aqueous electrolyte solution onto the electrodeposited AuNP surface were performed with a potentiometric method and calibrated by design of experiment (DOE). The resulting amperometric glucose biosensors was demonstrated to have a low detection limit (> 50 μM) and a wide linear range after optimization with AuNP electrodeposition.

Label-free and dual-amplified electrochemical detection of Hg2+ based on self-assembled DNA nanostructures and target-triggered exonuclease cleavage activity

2016 ◽  
Vol 40 (8) ◽  
pp. 6686-6691 ◽  
Author(s):  
Ting Bao ◽  
Wei Wen ◽  
Lei Shu ◽  
Xiuhua Zhang ◽  
Shengfu Wang
Keyword(s):  
Electrochemical Detection ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Dna Nanostructures ◽  
Label Free ◽  
Target Recycling ◽  
Cleavage Activity ◽  
Self Assembled ◽  
Exo Iii

An electrochemical biosensor for Hg2+ detection via HCR and Hg2+-triggered Exo III-assisted target recycling for signal amplification.

scholarly journals Doxorubicin Anticancer Drug Monitoring by ds-DNA-Based Electrochemical Biosensor in Clinical Samples

Micromachines ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 808
Author(s):  
Firouzeh Hassani Moghadam ◽  
Mohammad A. Taher ◽  
Hassan Karimi-Maleh
Keyword(s):  
Carbon Nanotubes ◽  
Detection Limit ◽  
Electrochemical Biosensor ◽  
Docking Study ◽  
Single Wall Carbon Nanotubes ◽  
Clinical Samples ◽  
Carbon Electrode ◽  
Molecular Docking Study ◽  
Voltammetric Sensing

In this research, glassy carbon electrode (GCE) amplified with single-wall carbon nanotubes (SWCNTs) and ds-DNA was fabricated and utilized for voltammetric sensing of doxorubicin with a low detection limit. In this technique, the reduction in guanine signal of ds-DNA in the presence of doxorubicin (DOX) was chosen as an analytical factor. The molecular docking study revealed that the doxorubicin drug interacted with DNA through intercalation mode, which was in agreement with obtained experimental results. The DOX detection performance of ds-DNA/SWCNTs/GCE was assessed at a concentration range of 1.0 nM–20.0 µM. The detection limit was found to be 0.6 nM that was comparable and even better (in many cases) than that of previous electrochemical reported sensors. In the final step, the ds-DNA/SWCNTs/GCE showed powerful ability for determination of the DOX in injection samples with acceptable recovery data.

Ultrasensitive strategy based on PtPd nanodendrite/nano-flower-like@GO signal amplification for the detection of long non-coding RNA

2015 ◽  
Vol 74 ◽  
pp. 214-221 ◽  
Author(s):  
Fei Liu ◽  
Guiming Xiang ◽  
Dongneng Jiang ◽  
Liqun Zhang ◽  
Xuemei Chen ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Non Coding Rna ◽  
Long Non Coding Rna

Bimetallic Pd–Pt supported graphene promoted enzymatic redox cycling for ultrasensitive electrochemical quantification of microRNA from cell lysates

The Analyst ◽  
2014 ◽  
Vol 139 (16) ◽  
pp. 3860-3865 ◽  
Author(s):  
Fang-Fang Cheng ◽  
Jing-Jing Zhang ◽  
Ting-Ting He ◽  
Jian-Jun Shi ◽  
E. S. Abdel-Halim ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Redox Cycling ◽  
Ultrasensitive Detection ◽  
Cell Lysates

A novel electrochemical biosensor with triple signal amplification for the ultrasensitive detection of miRNA was developed.

Sign in / Sign up

Export Citation Format

Share Document