Ultrasensitive photoelectrochemical biosensor for MiRNA-21 assay based on target-catalyzed hairpin assembly coupled with distance-controllable multiple signal amplification

2019 ◽  
Vol 55 (65) ◽  
pp. 9622-9625 ◽  
Author(s):  
Ming-Hui Zhu ◽  
Xiao-Mei Mu ◽  
Han-Mei Deng ◽  
Xia Zhong ◽  
Ruo Yuan ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Signal Amplification ◽  
Multiple Signal ◽  
Photoelectrochemical Biosensor ◽  
Catalyzed Hairpin Assembly

Here, with the target-catalyzed hairpin assembly generated dsDNA (HP1–HP2) to synchronously control the departure of quencher ferrocene and approach of sensitizer methylene blue, a distance-controllable multiple signal amplification based photoelectrochemical biosensor was proposed for MiRNA-21 assay.

A highly sensitive electrochemical microRNA-21 biosensor based on intercalating methylene blue signal amplification and a highly dispersed gold nanoparticles/graphene/polypyrrole composite

The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Methylene Blue ◽  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Highly Sensitive ◽  
Highly Dispersed ◽  
Polypyrrole Composite ◽  
Amplification Strategy ◽  
Dispersed Gold ◽  
Potential Tool

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.

A photoelectrochemical biosensor based on methylene blue sensitized Bi5O7I for sensitive detection of PSA

2021 ◽  
Author(s):  
Xuelian Xiang ◽  
Yanlin Wang ◽  
Yanhui Zhang ◽  
Ruo Yuan ◽  
Shangping Wei
Keyword(s):  
Methylene Blue ◽  
Sensitive Detection ◽  
Photoelectrochemical Biosensor ◽  
Signal Probe

Herein, bismuth oxyiodide (Bi5O7I) was used as a signal probe to construct an effective sensitization structure with methylene blue (MB), combined with protein conversion strategy, and a photoelectrochemical (PEC) biosensor was constructed...

Logic-signal-based multiplex detection of MiRNAs with high tension hybridization and multiple signal amplification

The Analyst ◽  
2020 ◽  
Vol 145 (12) ◽  
pp. 4314-4320
Author(s):  
Yaqin Tang ◽  
Xiao He ◽  
Rui Yuan ◽  
Xingming Liu ◽  
Yi Zhao ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Multiplex Detection ◽  
Detection Scheme ◽  
Multiple Signal ◽  
High Tension ◽  
Logic Signal ◽  
Mirna Detection ◽  
Signal Output

A multiplex miRNA detection scheme with simultaneous multiple signal output by single excitation has been reported.

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