Donor–acceptor conjugated polymer-based nanoparticles for highly effective photoacoustic imaging and photothermal therapy in the NIR-II window

2020 ◽  
Vol 56 (7) ◽  
pp. 1093-1096 ◽  
Author(s):  
Zuwu Wei ◽  
Fuli Xin ◽  
Jian Zhang ◽  
Ming Wu ◽  
Ting Qiu ◽  
...  

BDA nanoparticles exhibit excellent theranostic properties including an extremely high cancer cell killing ability, admirable tumor elimination efficiency (100%) and a remarkable photoacoustic imaging contrast enhancing ability.

2018 ◽  
Vol 10 (8) ◽  
pp. 7012-7021 ◽  
Author(s):  
Kaiwen Chang ◽  
Yubin Liu ◽  
Dehong Hu ◽  
Qiaofang Qi ◽  
Duyang Gao ◽  
...  

2017 ◽  
Vol 5 (26) ◽  
pp. 5128-5136 ◽  
Author(s):  
Yike Fu ◽  
Heng Liu ◽  
Zhaohui Ren ◽  
Xiang Li ◽  
Jie Huang ◽  
...  

CaTiO3:Yb,Er nanofibers, co-conjugated with Rose Bengal and gold nanorods, enable a synergistic photodynamic/photothermal phenomenon for superior cancer cell killing effect.


2019 ◽  
Vol 12 (03) ◽  
pp. 1930001 ◽  
Author(s):  
Xiaoju Men ◽  
Zhen Yuan

Photoacoustic imaging (PAI) is a hybrid imaging method based on photoacoustic (PA) effects, which is able to capture the structure, function, and molecular information of biological tissues with high resolution. To date, therapeutic techniques under the guidance of PAI have provided new strategies for accurate diagnosis and precise treatment of tumors. In particular, conjugated polymer nanoparticles have been extensively inspected for PA-based cancer theranostics largely due to their superior optical properties such as tunable spectrum and large absorption coefficient and their good biocompatibility, and abundant functional groups. This mini-review mainly focuses on the recent advances toward the development of novel conjugated polymer nanoparticles for PA-based multimodal imaging and cancer photothermal therapy.


2017 ◽  
Vol 1 (8) ◽  
pp. 1556-1562 ◽  
Author(s):  
Xiaolei Cai ◽  
Jie Liu ◽  
Weng Heng Liew ◽  
Yukun Duan ◽  
Junlong Geng ◽  
...  

We report organic nanoparticles for efficient photoacoustic imaging and photothermal therapy, based on the small molecule BTPETTQ which has a propeller structure and a donor–acceptor–donor configuration.


2015 ◽  
Vol 3 (6) ◽  
pp. 1135-1141 ◽  
Author(s):  
Guangxue Feng ◽  
Jie Liu ◽  
Junlong Geng ◽  
Bin Liu

We report conjugated polymers (CPs) microparticles (MPs) for selective cancer cell image-guided photothermal therapy. The CPMPs without surface functionalization can target MCF-7 cancer cells over NIH-3T3 normal cells, while nanoparticles need surface decoration to possess selectivity. Benefitting from large absorption, bright fluorescence, and efficient light-to-heat conversion of CPs, the fabricated MPs can selectively kill MCF-7 cells under NIR infrared laser irradiation.


RSC Advances ◽  
2020 ◽  
Vol 10 (26) ◽  
pp. 15221-15227
Author(s):  
Botao Qu ◽  
Xiaoyan Li ◽  
Xiaomin Zhang ◽  
Weihua Li ◽  
Ruiping Zhang

Herein we reported a biocompatible PVP-coated Sb2Se3 nanorods as PTT nanotheranostic agent, which is responsive to the light (808 and 980 nm) in NIR-I bio-windows and effective for photoacoustic imaging and photothermal destruction of cancer cell.


2021 ◽  
Vol 9 (14) ◽  
pp. 3153-3160
Author(s):  
Xin Jin ◽  
Xiaoyi Xing ◽  
Qingyuan Deng ◽  
Weixia Qing ◽  
Zhonghua Liu ◽  
...  

This work presents an efficient method of accessing DPP-SO that not only possess an excellent anti-tumour property but also regulates the photothermal performance of DPP-conjugated polymers by changing the heteroatom in the molecular skeleton.


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