Semi-rational hinge engineering: modulating the conformational transformation of glutamate dehydrogenase for enhanced reductive amination activity towards non-natural substrates

2020 ◽  
Vol 10 (10) ◽  
pp. 3376-3386 ◽  
Author(s):  
Xinjian Yin ◽  
Yayun Liu ◽  
Lijun Meng ◽  
Haisheng Zhou ◽  
Jianping Wu ◽  
...  
Keyword(s):  
Amino Acid ◽  
Glutamate Dehydrogenase ◽  
Acid Production ◽  
High Performance ◽  
Reductive Amination ◽  
Hinge Region ◽  
Conformational Transformation ◽  
Amino Acid Production ◽  
Optically Pure

The hinge region was identified to be a promising hotspot for activity engineering of GluDHs, providing a potent alternative for developing high-performance biocatalysts toward valuable optically pure l-amino acid production.

Sub-critical water hydrolysis of hog hair for amino acid production

2010 ◽  
Vol 101 (7) ◽  
pp. 2472-2476 ◽  
Author(s):  
M.B. Esteban ◽  
A.J. García ◽  
P. Ramos ◽  
M.C. Márquez
Keyword(s):  
Amino Acid ◽  
Acid Production ◽  
Amino Acid Production ◽  
Water Hydrolysis ◽  
Hydrolysis Of

Enzymology of Amino Acid Production

Biotechnology ◽  
2008 ◽  
pp. 503-560 ◽  
Author(s):  
Nobuyoshi Esaki ◽  
Shigeru Nakamori ◽  
Tatsuo Kurihara ◽  
Setsuo Furuyoshi ◽  
Kenji Soda
Keyword(s):  
Amino Acid ◽  
Acid Production ◽  
Amino Acid Production
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