Continuous-flow, well-mixed, microfluidic crystallization device for screening of polymorphs, morphology, and crystallization kinetics at controlled supersaturation

Lab on a Chip ◽  
2019 ◽  
Vol 19 (14) ◽  
pp. 2373-2382 ◽  
Author(s):  
Paria Coliaie ◽  
Manish S. Kelkar ◽  
Nandkishor K. Nere ◽  
Meenesh R. Singh

While the conventional screening techniques suffer from depletion of supersaturation, the continuous-flow microfluidic device screens crystalline materials at controlled supersaturation.

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Paria Coliaie ◽  
Manish S Kelkar ◽  
Marianne Langston ◽  
Chengxiang Liu ◽  
Neda Nazemifard ◽  
...  

A flow-controlled microfluidic device for parallel and combinatorial screening of crystalline materials can profoundly impact the discovery and development of active pharmaceutical ingredients and other crystalline materials. While the existing...


2007 ◽  
Vol 12 (5) ◽  
pp. 470-474 ◽  
Author(s):  
Thuan-Hieu Tran ◽  
Woo-Jin Chang ◽  
Young-Bum Kim ◽  
Yoon-Mo Koo ◽  
Eun-Ki Kim ◽  
...  

Lab on a Chip ◽  
2006 ◽  
Vol 6 (4) ◽  
pp. 561 ◽  
Author(s):  
Xunli Zhang ◽  
Jon M. Cooper ◽  
Paul B. Monaghan ◽  
Stephen J. Haswell

Lab on a Chip ◽  
2019 ◽  
Vol 19 (16) ◽  
pp. 2663-2668 ◽  
Author(s):  
Zhenqing Li ◽  
Ruixue Ju ◽  
Shinichi Sekine ◽  
Dawei Zhang ◽  
Songlin Zhuang ◽  
...  

A miniaturized device based on integrated continuous flow PCR and electrophoresis microfluidic chip was developed for diagnosis of pathogens. It dispensed with costly external precision syringe pump and can realize rapid DNA amplification and on-site PCR products detection.


2017 ◽  
Vol 184 (3) ◽  
pp. 835-841 ◽  
Author(s):  
Noa Cohen ◽  
Pooja Sabhachandani ◽  
Saheli Sarkar ◽  
Lindy Kahanovitz ◽  
Norman Lautsch ◽  
...  

2015 ◽  
Vol 4 (2) ◽  
pp. 150-153 ◽  
Author(s):  
Nhut Tran-Minh ◽  
Birgitte Kasin Hønsvall ◽  
Frank Karlsen

RSC Advances ◽  
2015 ◽  
Vol 5 (82) ◽  
pp. 66602-66610 ◽  
Author(s):  
Yankai Jia ◽  
Yukun Ren ◽  
Hongyuan Jiang

Efficient continuous-flow focusing of microparticles using induced-charge electroosmosis is presented and 3D AgPDMS electrodes are employed to avoid the negative effects of alternating current electroosmosis and dielectrophoresis.


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