scholarly journals Synthesis and biophysical properties of carbamate-locked nucleic acid (LNA) oligonucleotides with potential antisense applications

2019 ◽  
Vol 17 (21) ◽  
pp. 5341-5348 ◽  
Author(s):  
Cameron Thorpe ◽  
Sven Epple ◽  
Benjamin Woods ◽  
Afaf H. El-Sagheer ◽  
Tom Brown
Keyword(s):  
Nucleic Acid ◽  
Locked Nucleic Acid ◽  
Biophysical Properties

Carbamate-LNA oligonucleotides have improved biophysical properties for theraputic applications.

Synthesis and biological properties of triazole-linked locked nucleic acid

2017 ◽  
Vol 53 (63) ◽  
pp. 8906-8909 ◽  
Author(s):  
Vivek K. Sharma ◽  
Sunil K. Singh ◽  
Pranathi M. Krishnamurthy ◽  
Julia F. Alterman ◽  
Reka A. Haraszti ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Biological Properties ◽  
Locked Nucleic Acid ◽  
Biophysical Properties

We have synthesized and studied the biological and biophysical properties of triazole-linked ribo and xylo locked nucleic acid (LNA).

scholarly journals Synthesis and Biophysical Properties of C5-Functionalized LNA (Locked Nucleic Acid)

2014 ◽  
Vol 79 (11) ◽  
pp. 5047-5061 ◽  
Author(s):  
Pawan Kumar ◽  
Michael E. Østergaard ◽  
Bharat Baral ◽  
Brooke A. Anderson ◽  
Dale C. Guenther ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Locked Nucleic Acid ◽  
Biophysical Properties

Trinucleotide Cap Analogue Bearing a Locked Nucleic Acid Moiety: Synthesis, mRNA Modification, and Translation for Therapeutic Applications

2021 ◽  
Author(s):  
Annamalai Senthilvelan ◽  
Tyson Vonderfecht ◽  
Muthian Shanmugasundaram ◽  
Indra Pal ◽  
Jason Potter ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Locked Nucleic Acid ◽  
Acid Moiety ◽  
Therapeutic Applications

Solution Structure of a Locked Nucleic Acid Modified Quadruplex: Introducing the V4 Folding Topology

2009 ◽  
Vol 121 (17) ◽  
pp. 3145-3149 ◽  
Author(s):  
Jakob T. Nielsen ◽  
Khalil Arar ◽  
Michael Petersen
Keyword(s):  
Nucleic Acid ◽  
Solution Structure ◽  
Locked Nucleic Acid

i-Motif Formation with Locked Nucleic Acid (LNA)

2007 ◽  
Vol 119 (48) ◽  
pp. 9380-9382 ◽  
Author(s):  
Niti Kumar ◽  
Jakob T. Nielsen ◽  
Souvik Maiti ◽  
Michael Petersen
Keyword(s):  
Nucleic Acid ◽  
Locked Nucleic Acid

A Locked Nucleic Acid-Based Nanocrawler: Designed and Reversible Movement Detected by Multicolor Fluorescence

2013 ◽  
Vol 135 (7) ◽  
pp. 2423-2426 ◽  
Author(s):  
I. Kira Astakhova ◽  
Karol Pasternak ◽  
Meghan A. Campbell ◽  
Pankaj Gupta ◽  
Jesper Wengel
Keyword(s):  
Nucleic Acid ◽  
Locked Nucleic Acid ◽  
Multicolor Fluorescence

scholarly journals Locked Nucleic Acid Probe-Based Real-Time PCR Assay for the Rapid Detection of Rifampin-Resistant Mycobacterium tuberculosis

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0143444 ◽  
Author(s):  
Yong Zhao ◽  
Guilian Li ◽  
Chongyun Sun ◽  
Chao Li ◽  
Xiaochen Wang ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Nucleic Acid ◽  
Real Time ◽  
Real Time Pcr ◽  
Rapid Detection ◽  
Locked Nucleic Acid ◽  
Pcr Assay ◽  
Locked Nucleic Acid Probe
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