Intracellular delivery of liposome-encapsulated Finland trityl radicals for EPR oximetry

The Analyst ◽  
2020 ◽  
Vol 145 (14) ◽  
pp. 4964-4971 ◽  
Author(s):  
Xing Wang ◽  
Chao Peng ◽  
Ke He ◽  
Kaiyun Ji ◽  
Xiaoli Tan ◽  
...  

Intracellular delivery of TAM radical CT-03 is achieved using a liposome-based method, enabling simultaneous measurement of the intra/extracellular O2 levels and O2 consumption rates in combination of the extracellular TAM radical CT02-H.

2020 ◽  
Vol 85 (4) ◽  
pp. 2232-2246
Author(s):  
Hannes M. Wiesner ◽  
Dávid Z. Balla ◽  
Klaus Scheffler ◽  
Kâmil Uğurbil ◽  
Xiao‐Hong Zhu ◽  
...  

2005 ◽  
Vol 26 (3) ◽  
pp. 203-213 ◽  
Author(s):  
Julia A O'Hara ◽  
Huagang Hou ◽  
Eugene Demidenko ◽  
Roger J Springett ◽  
Nadeem Khan ◽  
...  

2014 ◽  
Vol 134 (3) ◽  
pp. 41-46
Author(s):  
Hironori Kumazaki ◽  
Munehiro Hiramatsu ◽  
Hisakazu Oguri ◽  
Seiki Inaba ◽  
Kazuhiro Hane

2019 ◽  
Author(s):  
Rohit Bhadoria ◽  
Kefeng Ping ◽  
Christer Lohk ◽  
Ivar Järving ◽  
Pavel Starkov

<div> <div> <div> <p>Conjugation techniques are central to improving intracellular delivery of bioactive small molecules. However, tracking and assessing the overall biological outcome of these constructs remains poorly understood. We addressed this issue by having developed a focused library of heterobivalent constructs based on Rho kinase inhibitors to probe various scenarios. By comparing induction of a phenotype of interest vs. cell viability vs. cellular uptake, we demonstrate that such conjugates indeed lead to divergent cellular outcomes. </p> </div> </div> </div>


1968 ◽  
Vol 8 (2) ◽  
pp. 288-306 ◽  
Author(s):  
G. C. Hufbauer

In the late nineteenth and early twentieth centuries, several Punjab Settlement Officers attempted to estimate food consumption rates. These estimates, based on direct observation and ad hoc guesses, were made partly out of academic curiosity, but more urgently, as an aid in establishing the land revenue (i.e., tax) rates. The pre-1926 estimates are summarized in Table I, expressed in pounds of wheat and other foodgrain consumption per person per year1. Broadly speaking, the later, more systemtic observers (e.g., Sir Ganga Ram and C. B. Barry), found lower consumption levels than the earlier observers. It was generally accepted that the rural populace ate better than urban dwellers. Despite the ingenuity of the early Settlement Officers, their compiled estimates suffer from all the difficulties of haphazard small sample observation. Given the revenue purpose of the estimates, they may be biased towards the able-bodied, economically active, population. Further, the very early estimates may have confused dry weight with cooked weight, including water.


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