Quantitative response to nitrite from field-induced decomposition of the chloride adduct of RDX by reactive stage tandem ion mobility spectrometry

The Analyst ◽  
2021 ◽  
Author(s):  
Umesh Chiluwal ◽  
Gary A. Eiceman
Keyword(s):  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Additional Dimension ◽  
Induced Decomposition ◽  
Chloride Adduct ◽  
Quantitative Response

An additional dimension of selectivity for the determination of RDX by ion mobility spectrometry (IMS) was introduced through field-induced decomposition of RDX·Cl− to NO2− on a spectral baseline free of interfering peaks.

scholarly journals Ion Mobility–Mass Spectrometry for Bioanalysis

Separations ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 33
Author(s):  
Xavier Garcia ◽  
Maria del Mar Sabaté ◽  
Jorge Aubets ◽  
Josep Maria Jansat ◽  
Sonia Sentellas
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Biological Samples ◽  
Ion Mobility Mass Spectrometry ◽  
Exogenous Compounds ◽  
Analytical Separation

This paper aims to cover the main strategies based on ion mobility spectrometry (IMS) for the analysis of biological samples. The determination of endogenous and exogenous compounds in such samples is important for the understanding of the health status of individuals. For this reason, the development of new approaches that can be complementary to the ones already established (mainly based on liquid chromatography coupled to mass spectrometry) is welcomed. In this regard, ion mobility spectrometry has appeared in the analytical scenario as a powerful technique for the separation and characterization of compounds based on their mobility. IMS has been used in several areas taking advantage of its orthogonality with other analytical separation techniques, such as liquid chromatography, gas chromatography, capillary electrophoresis, or supercritical fluid chromatography. Bioanalysis is not one of the areas where IMS has been more extensively applied. However, over the last years, the interest in using this approach for the analysis of biological samples has clearly increased. This paper introduces the reader to the principles controlling the separation in IMS and reviews recent applications using this technique in the field of bioanalysis.

scholarly journals Rapid determination of N-methylpyrrolidine in cefepime by combining direct infusion electrospray ionisation-time-of-flight mass spectrometry with field asymmetric waveform ion mobility spectrometry

2015 ◽  
Vol 7 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Robert W. Smith ◽  
Lisa B. Cox ◽  
Aswandi Yudin ◽  
James C. Reynolds ◽  
Mark Powell ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Rapid Determination ◽  
Time Of Flight ◽  
Asymmetric Waveform ◽  
Direct Infusion ◽  
Electrospray Ionisation ◽  
Flight Mass Spectrometry

FAIMS separation prior to mass spectrometry enables selective transmission of NMP in cefepime without interference from NMP formed by in-source CID.

Simultaneous determination of sertraline, imipramine and alprazolam in human plasma samples using headspace solid phase microextraction based on a nanostructured polypyrrole fiber coupled to ion mobility spectrometry

2020 ◽  
Vol 12 (7) ◽  
pp. 930-937 ◽  
Author(s):  
Erfan Barati ◽  
Naader Alizadeh
Keyword(s):  
Simultaneous Determination ◽  
Human Plasma ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Electrochemical Process ◽  
Plasma Samples ◽  
Spme Fiber

PPy-DBS was synthesized by an electrochemical process and used as a HS-SPME fiber for determination of antidepressants in plasma without derivatization steps.

scholarly journals Development of a methodology based on headspace-gas chromatography-ion mobility spectrometry for the rapid detection and determination of patin fish oil adulterated with palm oil

2020 ◽  
Vol 13 (10) ◽  
pp. 7524-7532 ◽  
Author(s):  
Anggita Rosiana Putri ◽  
Maria José Aliaño-González ◽  
Marta Ferreiro ◽  
Widiastuti Setyaningsih ◽  
Abdul Rohman ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Fish Oil ◽  
Palm Oil ◽  
Ion Mobility Spectrometry ◽  
Ion Mobility ◽  
Rapid Detection ◽  
Headspace Gas Chromatography ◽  
Headspace Gas
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