The potential neuroprotective role of Amphora coffeaeformis algae against monosodium glutamate-induced neurotoxicity in adult albino rats

2021 ◽  
Author(s):  
Shimaa Mohammad Yousof ◽  
Yasser Mahmoud Awad ◽  
Enas M. A. Mostafa ◽  
Marwa Mohamed Hosny ◽  
Marwa M. Anwar ◽  
...  

The current study provides a novel approach for treating monosodium glutamate neurotoxicity using safely cultivated Amphora coffeaeformis algae.

2014 ◽  
Vol 27 (4) ◽  
pp. 793 ◽  
Author(s):  
MonaAbd El Mawla Mohammed Soliman ◽  
AhmedAbozaid Ali ◽  
GhadaHassan El-Seify ◽  
HalaMohammed El Haroun

2013 ◽  
Vol 13 (4) ◽  
pp. 298-301 ◽  
Author(s):  
U.B. Ekaluo ◽  
E.V. Ikpeme ◽  
Y.B. Ibiang ◽  
O.S. Amaechina

Author(s):  
Ehab Tousson ◽  
Afaf El-Atrash ◽  
Yosra Karson

Background and Objective: Monosodium glutamate (MSG) is identified as an Accent that is used in the food industry as a flavour enhancer with an umami taste that intensifies the meaty, savoury flavour of food. The present study aimed at evaluating the protective and ameliorative role of rocket seeds extract against monosodium glutamate-induced hepatic renal toxicity and oxidative stress in the male rat. Materials and Methods: A total of 60 male adult albino rats were equally divided into six groups (G1, Control; G2, rocket seeds (RS); G3, ACCENT or MSG; G4, Co- treated (RS+MSG); G5, Post- treated (MSG+RS); G6, Self-treated MSG).  Results: Current results revealed that; a significant increase in serum ALT, AST, ALP, AFP, Urea, Creatinine, potassium ions, chloride ions, cholesterol, triglyceride, HDL, and LDL levels in MSG as compared to control and RS groups. In contrast; a significant decrease in serum albumin, total proteins, catalase, GSH and SOD in liver and kidney homogenates in MSG as compared to control and RS groups. Co- or post-treatment of MSG with rocket seeds improved this change in liver and kidney functions, with best results for co-treatment than post and self-treatment. Conclusion: These findings suggested that the misuse of monosodium glutamate may contribute to continuous hepatic and renal damage. This shows that the desired dose of monosodium glutamate can safely be used with grapes seed in improving hepatic and renal damage in monosodium glutamate in young rats.


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