Studies of the stability, nucleophilic substitution reactions, DNA/BSA interactions, cytotoxic activity, DFT and molecular docking of some tetra- and penta-coordinated gold(iii) complexes

2020 ◽  
Vol 44 (26) ◽  
pp. 11172-11187
Author(s):  
Snežana Radisavljević ◽  
Ana Đeković Kesić ◽  
Dušan Ćoćić ◽  
Ralph Puchta ◽  
Laura Senft ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Cytotoxic Activity ◽  
Nucleophilic Substitution ◽  
Substitution Reactions ◽  
Nucleophilic Substitution Reactions ◽  
Tu 5 ◽  
The Stability

The stability in water and at pH = 7.2, substitution reactions with Tu, 5’-GMP, GSH and l-Met, DNA/BSA interactions, cytotoxicity, DFT and molecular docking of gold(iii) complexes with phenanthroline derivatives as inert ligands were studied.

Homo- and hetero-dinuclear Pt(ii)/Pd(ii) complexes: studies of hydrolysis, nucleophilic substitution reactions, DNA/BSA interactions, DFT calculations, molecular docking and cytotoxic activity

2020 ◽  
Vol 49 (41) ◽  
pp. 14411-14431
Author(s):  
Dušan Ćoćić ◽  
Snežana Jovanović-Stević ◽  
Ratomir Jelić ◽  
Sanja Matić ◽  
Suzana Popović ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Dft Calculations ◽  
Cytotoxic Activity ◽  
Nucleophilic Substitution ◽  
Dinuclear Complexes ◽  
Substitution Reactions ◽  
Nucleophilic Substitution Reactions

Dinuclear complexes [Pd2(tpbd)Cl2]Cl2, [Pt2(tpbd)Cl2]Cl2 and [PdPt(tpbd)Cl2]Cl2 (tpbd = N,N,N′,N′-tetrakis(2-pyridylmethyl)benzene-1,4-diamine) have been synthesized and the kinetic, interactions with DNA/BSA and cytotoxic activity were studied.

New bimetallic palladium(ii) and platinum(ii) complexes: studies of the nucleophilic substitution reactions, interactions with CT-DNA, bovine serum albumin and cytotoxic activity

2016 ◽  
Vol 45 (31) ◽  
pp. 12444-12457 ◽  
Author(s):  
Snežana Jovanović ◽  
Katarina Obrenčević ◽  
Živadin D. Bugarčić ◽  
Iva Popović ◽  
Jelena Žakula ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Cytotoxic Activity ◽  
Nucleophilic Substitution ◽  
Bovine Serum ◽  
Substitution Reactions ◽  
Nucleophilic Substitution Reactions ◽  
Ct Dna ◽  
Bimetallic Palladium

Nucleophilic substitution reactions, interactions with CT-DNA, bovine serum albumin and cytotoxic activity of new bimetallic Pt(ii) and Pd(ii) complexes.

New dinuclear palladium(II) complexes: Studies of the nucleophilic substitution reactions, DNA/BSA interactions and cytotoxic activity

2017 ◽  
Vol 175 ◽  
pp. 67-79 ◽  
Author(s):  
Dušan Ćoćić ◽  
Snežana Jovanović ◽  
Marija Nišavić ◽  
Dejan Baskić ◽  
Danijela Todorović ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Nucleophilic Substitution ◽  
Substitution Reactions ◽  
Nucleophilic Substitution Reactions

The unexpected reactivity of 9-iodo-nido-carborane: from nucleophilic substitution reactions to the synthesis of tricobalt tris(dicarbollide) Na[4,4′,4′′-(MeOCH2CH2O)3-3,3′,3′′-Co3(μ3-O)(μ3-S)(1,2-C2B9H10)3]

2021 ◽  
Vol 50 (7) ◽  
pp. 2671-2688
Author(s):  
Marina Yu. Stogniy ◽  
Sergey A. Anufriev ◽  
Akim V. Shmal'ko ◽  
Sergey M. Antropov ◽  
Aleksei A. Anisimov ◽  
...  
Keyword(s):  
Nucleophilic Substitution ◽  
Substitution Reactions ◽  
Nucleophilic Substitution Reactions

An unusual reactivity of 9-iodo-nido-carborane [9-I-7,8-C2B9H11]− towards nucleophiles under strong basic conditions was revealed.

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