scholarly journals Effective atherosclerotic plaque inflammation inhibition with targeted drug delivery by hyaluronan conjugated atorvastatin nanoparticles

Nanoscale ◽  
2020 ◽  
Vol 12 (17) ◽  
pp. 9541-9556 ◽  
Author(s):  
Seyedmehdi Hossaini Nasr ◽  
Zahra Rashidijahanabad ◽  
Sherif Ramadan ◽  
Nate Kauffman ◽  
Narayanan Parameswaran ◽  
...  

Atherosclerosis is associated with inflammation in the arteries. Hyaluronan atorvastatin nanoparticle conjugate could target CD44 overexpressed in atherosclerotic plaques and significantly reduce plaque associated inflammation.

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