scholarly journals A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA

Nanoscale ◽  
2020 ◽  
Vol 12 (24) ◽  
pp. 12950-12957
Author(s):  
Marco Deiana ◽  
Karam Chand ◽  
Jan Jamroskovic ◽  
Rabindra Nath Das ◽  
Ikenna Obi ◽  
...  
Keyword(s):  
Selective Recognition ◽  
Site Specific ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Sensitivity And Selectivity ◽  
Self Assembled ◽  
A Site

A self-assembled light-up rotor probe with outstanding sensitivity and selectivity for the c-MYC promoter G-quadruplex DNA is reported.

Temperature-sensitive supramolecules self-assembled by G-quadruplex DNA

2010 ◽  
Vol 46 (1) ◽  
pp. 123-125 ◽  
Author(s):  
Hongxia Sun ◽  
Junfeng Xiang ◽  
Qiuju Zhou ◽  
Qianfan Yang ◽  
Guangzhi Xu ◽  
...  
Keyword(s):  
Temperature Sensitive ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Self Assembled

Selective recognition of c-MYC G-quadruplex DNA using prolinamide derivatives

2016 ◽  
Vol 14 (24) ◽  
pp. 5761-5767 ◽  
Author(s):  
Ajay Chauhan ◽  
Sushovan Paladhi ◽  
Manish Debnath ◽  
Jyotirmayee Dash
Keyword(s):  
Biological Evaluation ◽  
Selective Recognition ◽  
Design Synthesis ◽  
Quadruplex Dna ◽  
G Quadruplex

Herein we report the design, synthesis, biophysical and biological evaluation of triazole containing prolinamide derivatives as selectivec-MYCG-quadruplex binding ligands.

scholarly journals Self-assembled Pt2L2 boxes strongly bind G-quadruplex DNA and influence gene expression in cancer cells

2017 ◽  
Vol 46 (2) ◽  
pp. 329-332 ◽  
Author(s):  
O. Domarco ◽  
D. Lötsch ◽  
J. Schreiber ◽  
C. Dinhof ◽  
S. Van Schoonhoven ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cancer Cells ◽  
Quadruplex Dna ◽  
Dna Motifs ◽  
Size Dependent ◽  
G Quadruplex ◽  
Self Assembled ◽  
Influence Gene Expression

Pt(ii) boxes bind native and G-quadruplex DNA motifs in a size-dependent fashion and influence the expression of G-quadruplex forming genes.

scholarly journals Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Yi-Hwa Lin ◽  
Show-Mei Chuang ◽  
Pei-Ching Wu ◽  
Chun-Liang Chen ◽  
Sivakamavalli Jeyachandran ◽  
...  
Keyword(s):  
Selective Recognition ◽  
Quadruplex Dna ◽  
G Quadruplex

scholarly journals Small-Molecule-Based Self-Assembled Ligands for G-Quadruplex DNA Surface Recognition

ACS Omega ◽  
2017 ◽  
Vol 2 (10) ◽  
pp. 6619-6627 ◽  
Author(s):  
María del C. Rivera-Sánchez ◽  
Marilyn García-Arriaga ◽  
Gerard Hobley ◽  
Ana V. Morales-de-Echegaray ◽  
José M. Rivera
Keyword(s):  
Small Molecule ◽  
Quadruplex Dna ◽  
Surface Recognition ◽  
G Quadruplex ◽  
Self Assembled

Side-Chain-Dependent Binding of bis-Naphthalimide Self-Assembled Nanoparticles to G-Quadruplex DNA for Potential Anticancer Therapy

2020 ◽  
Vol 3 (2) ◽  
pp. 1339-1353
Author(s):  
Goutam Kulsi ◽  
Annie Agnes Suganya Samson ◽  
Baskaran Purushothaman ◽  
Joon Myong Song
Keyword(s):  
Anticancer Therapy ◽  
Side Chain ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Self Assembled

scholarly journals Copper(ii) l/d-valine-(1,10-phen) complexes target human telomeric G-quadruplex motifs and promote site-specific DNA cleavage and cellular cytotoxicity

2020 ◽  
Vol 49 (28) ◽  
pp. 9888-9899
Author(s):  
Farukh Arjmand ◽  
Surbhi Sharma ◽  
Sabiha Parveen ◽  
Loic Toupet ◽  
Zhen Yu ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Mtt Assay ◽  
Dna Cleavage ◽  
Cancer Cell Lines ◽  
Cellular Cytotoxicity ◽  
Site Specific ◽  
Quadruplex Dna ◽  
G Quadruplex

Chiral l-/d-valine-(1,10-phen)-Cu(ii) complexes that target G-quadruplex DNA were synthesized and thoroughly characterized. The cytotoxic activity of 1a and 1b on some of the notably important cancer cell lines was evaluated by MTT assay.

scholarly journals A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures

2021 ◽  
Author(s):  
Marco Deiana ◽  
Ikenna Obi ◽  
Måns Andreasson ◽  
Shanmugam Tamilselvi ◽  
Karam Chand ◽  
...  
Keyword(s):  
Selective Recognition ◽  
Quadruplex Dna ◽  
Dna Structures ◽  
Turn On ◽  
G Quadruplex
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