scholarly journals Water-based synthesis of photocrosslinked hyaluronic acid/polyvinyl alcohol membranes via electrospinning

RSC Advances ◽  
2020 ◽  
Vol 10 (52) ◽  
pp. 31271-31279
Author(s):  
Karine Cappuccio de Castro ◽  
Jonny Burga-Sánchez ◽  
Maria Gabriela Nogueira Campos ◽  
Lucia Helena Innocentini Mei
Keyword(s):  
Hyaluronic Acid ◽  
Polyvinyl Alcohol ◽  
Organic Solvent ◽  
Biomedical Applications ◽  
Electrospinning Method ◽  
Water Based

Homogeneous nanofibers and non-cytotoxic HA/PVA membranes were produced by conventional electrospinning method followed by photocrosslinking process, without using any organic solvent. The membranes showed great potential for biomedical applications.

scholarly journals Synthesis by gamma irradiation of hyaluronic acid-polyvinyl alcohol hydrogel for biomedical applications

2021 ◽  
Vol 67 (1) ◽  
pp. 58
Author(s):  
Fernanda Kamila Godoy-Alvarez ◽  
Maykel González-Torres ◽  
David M. Giraldo-Gomez ◽  
Roberto Sánchez-Sánchez ◽  
Mario A. Pérez-Díaz ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Polyvinyl Alcohol ◽  
Gamma Irradiation ◽  
Biomedical Applications

Production and characterization of biocompatible nanofibrous scaffolds made of β-sitosterol loaded polyvinyl alcohol/tragacanth gum composites

2021 ◽  
Author(s):  
Salim Albukhaty ◽  
Hassan Al-Karagoly ◽  
alireza allafchian ◽  
Seyed Amir Hossein Jalali ◽  
Thair Alkelabi ◽  
...  
Keyword(s):  
Polyvinyl Alcohol ◽  
Biomedical Applications ◽  
Sufficient Conditions ◽  
L929 Cell ◽  
Angle Measurement ◽  
Water Soluble ◽  
Normal Fibroblast ◽  
Tragacanth Gum ◽  
Nanofibrous Scaffolds ◽  
Poorly Water Soluble

Abstract Electrospun polyvinyl alcohol and Tragacanth Gum were used to develop nanofibrous scaffolds containing poorly water-soluble beta-sitosterol. Different Concentration and Ratio of Polymeric composite: (10%) of β-S concentration in (PVA) 8 %, (TG) 0.5%, and 1% respectively were added, prepared and electrospun. The methods have included four parameters (Solution concentration, feeding rate, voltage, and distance of the collector to the tip of the needle) for designing and compared the nanofibers' average diameters. The nanofibers collected were identified via SEM, FTIR, and XRD measurements. A contact angle measurement described the hydrophilicity of the scaffold. MTT test was assessed for obtained nanofibers by using L929 normal fibroblast cells. The %age of mechanical strength, porosity, and deterioration of the scaffolds was well discussed. The average nanofibre ranged from 63 ± 20 nm to 97 ± 46 nm in diameters. The nanofibers loaded with β-S were freely soluble in water and displayed a short release lag time. The dissolution was related to an immediate dissolution, submicron-level recrystallization of β-S with sufficient conditions for nanofibers for L929 cell culture that could be used in biomedical applications. It concluded that electrospinning is a promising technique for poorly water-soluble β-S formulations that could be used in biomedical applications.

scholarly journals Formation Behavior of Polyiodine Complex in Photocrosslinked Polyvinyl Alcohol Fiber Spun by Electrospinning Method

2018 ◽  
Vol 31 (4) ◽  
pp. 569-574
Author(s):  
Sho Fujisawa ◽  
Masumi Yamamoto ◽  
Daiki Kashiwai ◽  
Pedram Azari ◽  
Ying Ying Khaw ◽  
...  
Keyword(s):  
Polyvinyl Alcohol ◽  
Polyvinyl Alcohol Fiber ◽  
Electrospinning Method ◽  
Formation Behavior

Biological activity of electrochemically synthesized silver doped polyvinyl alcohol/graphene composite hydrogel discs for biomedical applications

2016 ◽  
Vol 104 ◽  
pp. 26-34 ◽  
Author(s):  
M.M. Abudabbus ◽  
I. Jevremović ◽  
A. Janković ◽  
A. Perić-Grujić ◽  
I. Matić ◽  
...  
Keyword(s):  
Biological Activity ◽  
Polyvinyl Alcohol ◽  
Biomedical Applications ◽  
Composite Hydrogel ◽  
Graphene Composite

scholarly journals Baicalein Nanofiber Scaffold Containing Hyaluronic Acid and Polyvinyl Alcohol: Preparation and Evaluation

2020 ◽  
Vol 50 (4) ◽  
pp. 1139-1146
Author(s):  
Kamel BACHIMAM ◽  
Ezgi EMUL ◽  
Necdet SAGLAM ◽  
Feza KORKUSUZ
Keyword(s):  
Hyaluronic Acid ◽  
Polyvinyl Alcohol ◽  
Nanofiber Scaffold ◽  
Preparation And Evaluation

The Potential Applications of Hyaluronic Acid Hydrogels in Biomedicine

Drug Research ◽  
2019 ◽  
Vol 70 (01) ◽  
pp. 6-11 ◽  
Author(s):  
Elham Ahmadian ◽  
Solmaz Maleki Dizaj ◽  
Aziz Eftekhari ◽  
Elaheh Dalir ◽  
Parviz Vahedi ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Biomedical Applications ◽  
Wound Repair ◽  
Stem Cell Differentiation ◽  
Clinical Applications ◽  
Cellular Behavior ◽  
Hydrogel Formation ◽  
Potential Applications ◽  
Basic Concepts ◽  
Elastic Sheets

AbstractHyaluronic acid (HA) is widely used in the biomedicine due to its biocompatibility, biodegradability, and nontoxic properties. It is crucial for cell signaling role during morphogenesis, inflammation, and wound repair. After hydrogel formation, HA easily is converted to elastic sheets in order to use in preclinical and clinical applications. In addition, HA-derived hydrogels are easily used as vectors for cell and medication in tissue repairing and regenerative medicine. Moreover, in comparison with other polymers, HA -based hydrogels play a key role in in cellular behavior, including stem cell differentiation. The current paper reviews both basic concepts and recent advances in the development of HA-based hydrogels for biomedical applications.

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