A Review of Enrichment Methods for Circulating Tumor Cells: from Single Modality to Hybrid Modality

The Analyst ◽  
2021 ◽  
Author(s):  
Yi Zhang ◽  
Yifu Li ◽  
Zhongchao Tan

Circulating tumor cell (CTC) analysis as a liquid biopsy can be used for early diagnosis of cancer, evaluate cancer progression, and assess treatment efficacy. Enrichment of CTC from patient blood...

RSC Advances ◽  
2019 ◽  
Vol 9 (46) ◽  
pp. 26729-26733 ◽  
Author(s):  
Ya Zhu ◽  
Jialing Han ◽  
Qian Zhang ◽  
Zhou Zhao ◽  
Jin Wang ◽  
...  

Human NAD(P)H:quinone oxidoreductase (hNQO1) can be used as a biomarker for the early diagnosis of cancer.


2021 ◽  
Vol 5 (5) ◽  
pp. 41-46
Author(s):  
Quan Zheng ◽  
Ying Xiong ◽  
Jinku Zhang

Epidemiological data show that the incidence rate of cholangiocarcinoma (CCA) has been increasing over the past 20 years. Due to its concealment of clinical manifestations, most patients are diagnosed with CCA at a late stage. On this premise, this review not only discusses the research progress related to CCA diagnosis, but also focuses on the concept of circulating tumor cell (CTC), its evaluation value, application, and prospects for the early diagnosis of extrahepatic cholangiocarcinoma.


Cells ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 130 ◽  
Author(s):  
Ines Stevic ◽  
Gustav Buescher ◽  
Franz Lennard Ricklefs

Extracellular vesicles (EVs) are a heterogeneous group of membrane-enclosed vesicles made of a phospholipid bilayer and are secreted by all cell types. EVs are present in a variety of body fluids containing proteins, DNA, RNA species, and lipids, and play an important role in cell- to-cell communication and are worth being considered as biomarkers for both early diagnosis of cancer patients and real-time monitoring of treatment response. Recently, emerging evidence verified EVs to have crucial roles in cancer progression and metastasis and a great potential in therapeutic applications. In this review, we discuss the potential of EVs in monitoring the efficacy of cancer therapies.


2017 ◽  
Vol 112 (3) ◽  
pp. 461a ◽  
Author(s):  
Sung Cheol Kim ◽  
Navneet Dogra ◽  
Benjamin H. Wunsch ◽  
Joshua T. Smith ◽  
Stacey M. Gifford ◽  
...  

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