A Dual-Channel Hill-Type Small-Molecule pH Probe

In this paper we report a unique approach to control the DNA interactions, cellular uptake and cellular localisation of a small molecule. We have designed rotaxanes that include a luminescent DNA binder, a macrocycle that modulates the DNA binding and a stopper that can be cleaved by either light or the activity of an enzyme.

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Highly Sensitive Hill-Type Small-Molecule pH Probe That Recognizes the Reversed pH Gradient of Cancer Cells

Analytical Chemistry ◽

10.1021/acs.analchem.8b00218 ◽

2018 ◽

Vol 90 (9) ◽

pp. 5803-5809 ◽

Cited By ~ 18

Author(s):

Xiao Luo ◽

Haotian Yang ◽

Haolu Wang ◽

Zhiwei Ye ◽

Zhongneng Zhou ◽

...

Keyword(s):

Cancer Cells ◽

Small Molecule ◽

Ph Gradient ◽

Ph Probe ◽

Highly Sensitive

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Rotaxanes as Cages to Control DNA Binding, Cytotoxicity and Cellular Uptake of a Small Molecule

10.26434/chemrxiv.13249643 ◽

2020 ◽

Author(s):

Timothy Kench ◽

Peter A. Summers ◽

Marina K. Kuimova ◽

James Lewis ◽

Ramon Vilar

Keyword(s):

Dna Binding ◽

Cellular Uptake ◽

Small Molecule ◽

Dna Interactions ◽

Cellular Localisation ◽

Unique Approach

In this paper we report a unique approach to control the DNA interactions, cellular uptake and cellular localisation of a small molecule. We have designed rotaxanes that include a luminescent DNA binder, a macrocycle that modulates the DNA binding and a stopper that can be cleaved by either light or the activity of an enzyme.

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Characterization of intergranular cuprous oxide in polycrystalline YBa2Cu3O7-x

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100106466 ◽

1988 ◽

Vol 46 ◽

pp. 880-881

Author(s):

Bradley L. Thiel ◽

Chan Han R. P. ◽

Kurosky L. C. Hutter ◽

I. A. Aksay ◽

Mehmet Sarikaya

Keyword(s):

Grain Boundary ◽

Cuprous Oxide ◽

Room Temperature ◽

Boundary Phase ◽

Spectroscopic Techniques ◽

Transition Width ◽

Practical Applications ◽

Thin Foils ◽

Superconducting Oxides

The identification of extraneous phases is important in understanding of high Tc superconducting oxides. The spectroscopic techniques commonly used in determining the origin of superconductivity (such as RAMAN, XPS, AES, and EXAFS) are surface-sensitive. Hence a grain boundary phase several nanometers thick could produce irrelevant spectroscopic results and cause erroneous conclusions. The intergranular phases present a major technological consideration for practical applications. In this communication we report the identification of a Cu2O grain boundary phase which forms during the sintering of YBa2Cu3O7-x (1:2:3 compound).Samples are prepared using a mixture of Y2O3. CuO, and BaO2 powders dispersed in ethanol for complete mixing. The pellets pressed at 20,000 psi are heated to 950°C at a rate of 5°C per min, held for 1 hr, and cooled at 1°C per min to room temperature. The samples show a Tc of 91K with a transition width of 2K. In order to prevent damage, a low temperature stage is used in milling to prepare thin foils which are then observed, using a liquid nitrogen holder, in a Philips 430T at 300 kV.

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A privileged ternary blend enabling non-fullerene organic photovoltaics with over 14% efficiency

Journal of Materials Chemistry C ◽

10.1039/d0tc02778b ◽

2020 ◽

Vol 8 (43) ◽

pp. 15135-15141

Author(s):

Jing Yan ◽

Yuan-Qiu-Qiang Yi ◽

Jianqi Zhang ◽

Huanran Feng ◽

Yanfeng Ma ◽

...

Keyword(s):

Small Molecule ◽

Organic Photovoltaics ◽

Power Conversion ◽

Ternary Blend ◽

Conversion Efficiencies

Two non-fullerene small molecule acceptors, NT-4F and NT-4Cl, were designed and synthesized. Power conversion efficiencies of 11.44% and 14.55% were achieved for NT-4Cl-based binary and ternary devices, respectively.

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