Hepatoprotective effect of piceatannol against carbon tetrachloride-induced liver fibrosis in mice

2021 ◽  
Author(s):  
Wei-Lun Hung ◽  
Yi-Ting Hsiao ◽  
Yi-Shiou Chiou ◽  
Nagabhushanam Kalyanam ◽  
Chi-Tang Ho ◽  
...  

Piceatannol (3,5,3’,4’-trans-tetrahydroxystilbene) is a natural analog and a metabolite of resveratrol present in grapes and red wine. Previous studies have reported that piceatannol exerts a broad spectrum of health benefits...

2021 ◽  
Vol 13 (6) ◽  
pp. 1428-1436
Author(s):  
Raden Joko Kuncoroningrat Susilo ◽  
Dwi Winarni ◽  
Saikhu Akhmad Husen ◽  
Suhailah Hayaza ◽  
Sri Puji Astuti Wahyuningsih ◽  
...  

2021 ◽  
Author(s):  
Wei-Lun Hung ◽  
Yi-Ting Hsiao ◽  
Yi-Shiou Chiou ◽  
Kalyanam Nagabhushanam ◽  
Chi-Tang Ho ◽  
...  

Correction for ‘Hepatoprotective effect of piceatannol against carbon tetrachloride-induced liver fibrosis in mice’ by Wei-Lun Hung et al., Food Funct., 2021, DOI: 10.1039/D1FO02545G.


2014 ◽  
Vol 568-570 ◽  
pp. 1934-1939
Author(s):  
Wen Jun Sun ◽  
Hai Bo He ◽  
Jun Zhi Wang ◽  
Ling Wu ◽  
Fan Cheng ◽  
...  

To analysis the main component of Laetiporus sulphureus primary separation product (LSPSP) and observe the hepatoprotective effect of LSPSP. Silica column and HPLC was adopted to isolate main constituents from LSPSP. The main components were analyzed and identified by HPLC and HNMR. And then its hepatoprotective effect was evaluated, we used Sprague-Dawley rats as experimental rats, and made hepatic fibrosis models induced by carbon tetrachloride (CCl4).The hepatoprotective effects of SPSP on hepatic fibrosis of rats were evaluated by content of AST and ALT, levels of liver cell injury and degree of liver fibrosis. In the study, we found that LSPSP mainly contains eburicoic acid and trametenolic acid B. After treatment with LSPSP, the levels of serum AST and ALT significantly decreased, alleviated liver cell damage, reduced the collagen deposition in the liver tissue, and then inhibited liver fibrosis. Our studies indicated that LSPSP main components areeburicoic acid and trametenolic acid B, it exerted beneficially hepatoprotective effects on the CCl4 induced hepatic fibrosis.


Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
YJ Moon ◽  
WC Lee ◽  
SJ Kim ◽  
ST Oh ◽  
EJ Shin ◽  
...  

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