Chemical Catalyst-Promoted Photooxygenation of Amyloid Proteins

2021 ◽  
Author(s):  
Youhei Sohma ◽  
Taka Sawazaki ◽  
Motomu Kanai
Keyword(s):  
Higher Order ◽  
Misfolded Proteins ◽  
Beta Sheet ◽  
Amyloid Proteins ◽  
Aggregation Processes ◽  
Order Structures

Misfolded proteins produce aberrant fibrillar aggregates, called amyloid, that contain cross-beta-sheet higher order structures. The species generated in the aggregation processes (i.e., oligomers, protofibrils, and fibrils) are cytotoxic and can...

Role of the Structural Characteristics of Dendrimers in the Manifestation of the Antiamyloid Properties

INEOS OPEN ◽  
2020 ◽  
Vol 3 ◽  
Author(s):  
S. A. Sorokina ◽  
◽  
Yu. Yu. Stroilova ◽  
V. I. Muronets ◽  
Z. B. Shifrina ◽  
...  
Keyword(s):  
Neurodegenerative Diseases ◽  
Structural Characteristics ◽  
Short Review ◽  
External Factors ◽  
Amyloid Aggregation ◽  
Amyloid Proteins ◽  
Molecular Parameters ◽  
Amyloid Aggregates ◽  
Aggregation Processes

Among the compounds able to efficiently inhibit the amyloid aggregation of proteins and decompose the amyloid aggregates that cause neurodegenerative diseases, of particular interest are dendrimers, which represent individual macromolecules with the hypercrosslinked architectures and given molecular parameters. This short review outlines the peculiarities of the antiamyloid activity of dendrimers and discusses the effect of dendrimer structures and external factors on their antiamyloid properties. The potential of application of dendrimers in further investigations on the aggregation processes of amyloid proteins as the compounds that exhibit the remarkable antiamyloid activity is evaluated.

Microsized Structures Fabricated with Nanoparticles as Building Blocks

1998 ◽  
Vol 536 ◽  
Author(s):  
Yongchi Tian ◽  
A. D. Dinsmore ◽  
S. B. Qadri ◽  
B. R. Ratna
Keyword(s):  
Radial Growth ◽  
Building Blocks ◽  
Higher Order ◽  
Surfactant Templating ◽  
Order Structures

AbstractHere we report a nanoparticulate route to Y2O3 nanofibers (~50 nm in diameter and a few micrometers in length) and for the radial growth of ZnS spheres (200-800 nm diameter). Well-defined higher order structures are developed upon thermostatically aging the dispersions of monomeric nanocrystals. The shapes of the “macromolecules„ are correlated to primary monomeric nanocrystallites, the growing time and temperature, and surfactant templating agents. It is anticipated that this approach should inspire fabrication of nanoparticulate structures by using primary nanoparticles as monomers.

External Correlates of the Personality Assessment Inventory Higher Order Structures

2013 ◽  
Vol 95 (4) ◽  
pp. 432-434 ◽  
Author(s):  
Jenelle Slavin-Mulford ◽  
Samuel Justin Sinclair ◽  
Johanna Malone ◽  
Michelle Stein ◽  
Iruma Bello ◽  
...  
Keyword(s):  
Personality Assessment ◽  
Personality Assessment Inventory ◽  
Higher Order ◽  
Order Structures

Monte Carlo Approach in Assessing Damage in Higher Order Structures of DNA

1994 ◽  
pp. 225-241 ◽  
Author(s):  
Aloke Chatterjee ◽  
James B. Schmidt ◽  
William R. Holley
Keyword(s):  
Monte Carlo ◽  
Higher Order ◽  
Monte Carlo Approach ◽  
Order Structures

scholarly journals The Chlamydia trachomatis PmpD adhesin forms higher order structures through disulphide-mediated covalent interactions

PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0198662 ◽  
Author(s):  
Wayne Paes ◽  
Adam Dowle ◽  
Jamie Coldwell ◽  
Andrew Leech ◽  
Tim Ganderton ◽  
...  
Keyword(s):  
Chlamydia Trachomatis ◽  
Higher Order ◽  
Covalent Interactions ◽  
Order Structures

Potential grouping of nodes induced by higher-order structures in complex networks

2021 ◽  
Vol 31 (12) ◽  
pp. 123115
Author(s):  
Slobodan Maletić ◽  
Miroslav Andjelković ◽  
Milan Rajković
Keyword(s):  
Complex Networks ◽  
Higher Order ◽  
Order Structures
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