scholarly journals Engineering the biomimetic cofactors of NMNH for cytochrome P450 BM3 based on binding conformation refinement

RSC Advances ◽  
2021 ◽  
Vol 11 (20) ◽  
pp. 12036-12042
Author(s):  
Yao Liu ◽  
Yalong Cong ◽  
Chuanxi Zhang ◽  
Bohuan Fang ◽  
Yue Pan ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Rational Design ◽  
Design Strategy ◽  
Efficient Utilization ◽  
P450 Bm3 ◽  
Binding Conformation ◽  
Cytochrome P450 Bm3

A rational design strategy was proposed to improve the efficient utilization of alternative biomimetic cofactor by P450 BM3 enzyme.

The Role of Protein Plasticity in Computational Rationalization Studies on Regioselectivity in Testosterone Hydroxylation by Cytochrome P450 BM3 Mutants

2012 ◽  
Vol 13 (2) ◽  
pp. 155-166 ◽  
Author(s):  
Stephanie B.A. de Beer ◽  
Laura A.H. van Bergen ◽  
Karlijn Keijzer ◽  
Vanina Rea ◽  
Harini Venkataraman ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
P450 Bm3 ◽  
Cytochrome P450 Bm3 ◽  
Testosterone Hydroxylation

scholarly journals Reduction of Dioxygen Catalyzed by Pyrene-Wired Heme Domain Cytochrome P450 BM3 Electrodes

2004 ◽  
Vol 126 (33) ◽  
pp. 10218-10219 ◽  
Author(s):  
Andrew K. Udit ◽  
Michael G. Hill ◽  
V. Garrett Bittner ◽  
Frances H. Arnold ◽  
Harry B. Gray
Keyword(s):  
Cytochrome P450 ◽  
P450 Bm3 ◽  
Heme Domain ◽  
Cytochrome P450 Bm3

Application of cytochrome P450 BM3 mutants as biocatalysts for the profiling of estrogen receptor binding metabolites of the mycotoxin zearalenone

Xenobiotica ◽  
2010 ◽  
Vol 41 (1) ◽  
pp. 59-70 ◽  
Author(s):  
Jelle Reinen ◽  
Livia L. Kalma ◽  
Selina Begheijn ◽  
Ferry Heus ◽  
Jan N.M. Commandeur ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Cytochrome P450 ◽  
Receptor Binding ◽  
P450 Bm3 ◽  
Estrogen Receptor Binding ◽  
Cytochrome P450 Bm3

scholarly journals Formation of Transient Oxygen Complexes of Cytochrome P450 BM3 and Nitric Oxide Synthase under High Pressure

2003 ◽  
Vol 85 (5) ◽  
pp. 3303-3309 ◽  
Author(s):  
Stéphane Marchal ◽  
Hazel Mary Girvan ◽  
Antonius C.F. Gorren ◽  
Bernd Mayer ◽  
Andrew William Munro ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
High Pressure ◽  
Cytochrome P450 ◽  
Nitric Oxide Synthase ◽  
P450 Bm3 ◽  
Cytochrome P450 Bm3 ◽  
Oxide Synthase ◽  
Oxygen Complexes

Activation of the anticancer drugs cyclophosphamide and ifosfamide by cytochrome P450 BM3 mutants

2015 ◽  
Vol 232 (1) ◽  
pp. 182-192 ◽  
Author(s):  
Galvin Vredenburg ◽  
Shalenie den Braver-Sewradj ◽  
Barbara M.A. van Vugt-Lussenburg ◽  
Nico P.E. Vermeulen ◽  
Jan N.M. Commandeur ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Anticancer Drugs ◽  
P450 Bm3 ◽  
Cytochrome P450 Bm3

scholarly journals Structural analysis of Cytochrome P450 BM3 mutant M11 in complex with dithiothreitol

PLoS ONE ◽  
2019 ◽  
Vol 14 (5) ◽  
pp. e0217292 ◽  
Author(s):  
Karla Frydenvang ◽  
Marlies C. A. Verkade-Vreeker ◽  
Floor Dohmen ◽  
Jan N. M. Commandeur ◽  
Maria Rafiq ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Structural Analysis ◽  
P450 Bm3 ◽  
Cytochrome P450 Bm3

High throughput assay for cytochrome P450 BM3 for screening libraries of substrates and combinatorial mutants

2002 ◽  
Vol 17 (1-2) ◽  
pp. 119-131 ◽  
Author(s):  
Georgia Eleni Tsotsou ◽  
Anthony Edward George Cass ◽  
Gianfranco Gilardi
Keyword(s):  
Cytochrome P450 ◽  
High Throughput ◽  
P450 Bm3 ◽  
Cytochrome P450 Bm3 ◽  
High Throughput Assay
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