scholarly journals Semi-synthetic puwainaphycin/minutissamide cyclic lipopeptides with improved antifungal activity and limited cytotoxicity

RSC Advances ◽  
2021 ◽  
Vol 11 (49) ◽  
pp. 30873-30886
Author(s):  
Jan Hájek ◽  
Sebastian Bieringer ◽  
Kateřina Voráčová ◽  
Markéta Macho ◽  
Kumar Saurav ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Antifungal Activity ◽  
Fatty Acid Moiety ◽  
Acid Moiety ◽  
Cyclic Lipopeptides ◽  
Free Hydroxyl

Both the substitution of free hydroxyl substituents and extending/branching of the fatty acid moiety improved the antifungal potency and limits the cytotoxicity of cyanobacterial cyclic lipopeptides puwainaphycin/minutissamides.

A novel highly unsaturated fatty acid moiety of lipo-oligosaccharide signals determines host specificity of Rhizobium

Nature ◽  
1991 ◽  
Vol 354 (6349) ◽  
pp. 125-130 ◽  
Author(s):  
Herman P. Spaink ◽  
Douglas M. Sheeley ◽  
Anton A. N. van Brussel ◽  
John Glushka ◽  
William S. York ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Host Specificity ◽  
Unsaturated Fatty Acid ◽  
Highly Unsaturated Fatty Acid ◽  
Fatty Acid Moiety ◽  
Acid Moiety

scholarly journals Phospholipid requirements for the reconstitution of complex-III vesicles exhibiting controlled electron transport

1981 ◽  
Vol 194 (3) ◽  
pp. 783-787 ◽  
Author(s):  
B D Nelson ◽  
S Fleischer
Keyword(s):  
Escherichia Coli ◽  
Fatty Acid ◽  
Electron Transport ◽  
Respiratory Control ◽  
Complex Iii ◽  
Fatty Acid Moiety ◽  
Head Group ◽  
Acid Moiety ◽  
Transport Control ◽  
Acidic Phospholipids

Phospholipid requirements for the reconstitution of Complex-III vesicles exhibiting respiratory control (electron-transport control) were studied. Vesicles prepared from pure phosphatidylethanolamine gave maximal control ratios. Phosphatidylcholine alone did not support respiratory control, although these vesicles were capable of maintaining stable K+-diffusion gradients. Apparently Complex III cannot insert into a bilayer of phosphatidylcholine. Formation of mixed phosphatidylcholine/phosphatidylethanolamine (6:1, w/w) vesicles was sufficient, however, to allow Complex-III insertion and to restore respiratory control. Mixtures of acidic phospholipids with either phosphatidylethanolamine or phosphatidylcholine did not improve respiratory control over that obtained with pure phosphatidylethanolamine. Phosphatidylethanolamine from bovine heart mitochondria, soya beans or Escherichia coli was equally effective in reconstituting respiratory control, suggesting that the specificity is referable to the head group and not to the fatty-acid moiety.

scholarly journals Sinorhizobium meliloti acpXLMutant Lacks the C28 Hydroxylated Fatty Acid Moiety of Lipid A and Does Not Express a Slow Migrating Form of Lipopolysaccharide

2003 ◽  
Vol 278 (15) ◽  
pp. 12946-12954 ◽  
Author(s):  
Larissa A. Sharypova ◽  
Karsten Niehaus ◽  
Heiko Scheidle ◽  
Otto Holst ◽  
Anke Becker
Keyword(s):  
Fatty Acid ◽  
Sinorhizobium Meliloti ◽  
Lipid A ◽  
Fatty Acid Moiety ◽  
Acid Moiety

Origin of the Fatty Acid Moiety of Fetal Serum Phospholipids in Rats

Neonatology ◽  
1974 ◽  
Vol 24 (5-6) ◽  
pp. 292-297 ◽  
Author(s):  
L. Hummel ◽  
W. Schirrmeister ◽  
T. Zimmermann
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Moiety ◽  
Acid Moiety ◽  
Fetal Serum ◽  
Serum Phospholipids

ChemInform Abstract: Synthesis of a Highly Unsaturated Fatty Acid Moiety of Lipo- Oligosaccharides Determining Host-Specificity in Rhizobium.

ChemInform ◽  
2010 ◽  
Vol 23 (48) ◽  
pp. no-no
Author(s):  
R. VERDUYN ◽  
R. M. LAGAS ◽  
C. E. DREEF ◽  
G. A. VAN DER MAREL ◽  
J. H. VAN BOOM
Keyword(s):  
Fatty Acid ◽  
Host Specificity ◽  
Unsaturated Fatty Acid ◽  
Highly Unsaturated Fatty Acid ◽  
Fatty Acid Moiety ◽  
Acid Moiety

SOME PHYSIOLOGIC CHARACTERISTICS OF ESTERS OF CETYL ALCOHOL

1959 ◽  
Vol 37 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Doris Howes Calloway ◽  
George W. Kurtz ◽  
Rorert B. Potts
Keyword(s):  
Energy Source ◽  
Fatty Acids ◽  
Fatty Acid ◽  
Free Fatty Acids ◽  
Butyric Acid ◽  
Cetyl Alcohol ◽  
Fatty Acid Moiety ◽  
Acid Moiety ◽  
Cetyl Palmitate ◽  
Acid Esters

Palmitic, oleic, and butyric acid esters of cetyl alcohol were fed to mature rats. Cetyl palmitate was quantitatively excreted in the feces and produced no physiologic aberration. While cetyl oleate was 75% absorbable, it was of little value as an energy source and was partially excreted through the skin. Feeding of cetyl butyrate also induced seborrhea. Data on free fatty acids in gastrointestinal contents and on the specificity of seborrheic lipids indicate that cetyl esters are largely absorbed without hydrolysis, if the fatty acid moiety is readily absorbable, and excreted by way of the skin without modification.

scholarly journals Modulation of peritoneal macrophage activity by the saturation state of the fatty acid moiety of phosphatidylcholine

2009 ◽  
Vol 42 (7) ◽  
pp. 599-605 ◽  
Author(s):  
F.C.C. Grando ◽  
C.A. Felício ◽  
A. Twardowschy ◽  
F.M. Paula ◽  
V.G. Batista ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Peritoneal Macrophage ◽  
Fatty Acid Moiety ◽  
Acid Moiety ◽  
Saturation State ◽  
Macrophage Activity
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