Fibrin binds to collagen and provides a bridge for αVβ3 integrin-dependent contraction of collagen gels
Keyword(s):
The putative functions of extravascular fibrin in pathologies are poorly characterized. We show that fibrinogen binds specifically to a defined protein-binding site of the native collagen. Through this binding, fibrin provides an interface matrix allowing αVβ3 integrin-mediated collagen gel contraction.
1979 ◽
Vol 254
(16)
◽
pp. 7724-7729
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Keyword(s):
1987 ◽
Vol 7
(12)
◽
pp. 4400-4406
◽
2019 ◽
Vol 59
(7)
◽
pp. 3136-3143
Keyword(s):
Keyword(s):