Immunohistochemical analysis of p186 in normal and trasformed human tissues

1996 ◽  
Vol 24 (2) ◽  
pp. 306S-306S
Author(s):  
PAGANI ROBERTO ◽  
PORCELLI BRUNETTA ◽  
FROSI BARBARA ◽  
PIZZICHINI MARIA ◽  
VERNILLO REMO ◽  
...  
Author(s):  
Davide Vecchiotti ◽  
Daniela Verzella ◽  
Daria Capece ◽  
Jessica Cornice ◽  
Mauro Di Vito Nolfi ◽  
...  

2001 ◽  
Vol 92 (6) ◽  
pp. 856-860 ◽  
Author(s):  
Achim A. Jungbluth ◽  
Yao-Tseng Chen ◽  
Elisabeth Stockert ◽  
Klaus J. Busam ◽  
Denise Kolb ◽  
...  

Author(s):  
Feria Hikmet ◽  
Loren Méar ◽  
Åsa Edvinsson ◽  
Patrick Micke ◽  
Mathias Uhlén ◽  
...  

ABSTRACTThe novel SARS-coronavirus 2 (SARS-CoV-2) poses a global challenge on healthcare and society. For understanding the susceptibility for SARS-CoV-2 infection, the cell type-specific expression of the host cell surface receptor is necessary. The key protein suggested to be involved in host cell entry is Angiotensin I converting enzyme 2 (ACE2). Here, we report the expression pattern of ACE2 across >150 different cell types corresponding to all major human tissues and organs based on stringent immunohistochemical analysis. The results were compared with several datasets both on the mRNA and protein level. ACE2 expression was mainly observed in enterocytes, renal tubules, gallbladder, cardiomyocytes, male reproductive cells, placental trophoblasts, ductal cells, eye and vasculature. In the respiratory system, the expression was limited, with no or only low expression in a subset of cells in a few individuals, observed by one antibody only. Our data constitutes an important resource for further studies on SARS-CoV-2 host cell entry, in order to understand the biology of the disease and to aid in the development of effective treatments to the viral infection.


2003 ◽  
Vol 88 (3) ◽  
pp. 635-642 ◽  
Author(s):  
James B. DuHadaway ◽  
Frank J. Lynch ◽  
Shawn Brisbay ◽  
Carlos Bueso-Ramos ◽  
Patricia Troncoso ◽  
...  

1997 ◽  
Vol 30 (3) ◽  
pp. 285
Author(s):  
L. Terzuoli ◽  
B. Frosi ◽  
B. Porcelli ◽  
F. Carlucci ◽  
C. Minacci ◽  
...  

2007 ◽  
Vol 105 (1-5) ◽  
pp. 115-123 ◽  
Author(s):  
Kyle W. Selcer ◽  
Heidi M. DiFrancesca ◽  
Abhinav B. Chandra ◽  
Pui-Kai Li

Apmis ◽  
1999 ◽  
Vol 107 (7-12) ◽  
pp. 1013-1019 ◽  
Author(s):  
Sug Hyung Lee ◽  
Min Sun Shin ◽  
Won Sang Park ◽  
Su Young Kim ◽  
Seung Myung Dong ◽  
...  

1991 ◽  
Vol 47 (2) ◽  
pp. 193-201 ◽  
Author(s):  
Raphe R. S. Kantor ◽  
Steven L. Giardina ◽  
Armando Bartolazzi ◽  
Allen J. Townsend ◽  
Charles E. Myers ◽  
...  

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