Alcohol Withdrawal and Hypertension: Evidence for a Kidney Abnormality

1985 ◽  
Vol 69 (2) ◽  
pp. 239-240 ◽  
Author(s):  
Sergio De Marchi ◽  
Emanuela Cecchin
Keyword(s):  
Blood Pressure ◽  
Plasma Renin Activity ◽  
Alcohol Withdrawal ◽  
Plasma Renin ◽  
Renin Activity ◽  
Withdrawal Symptoms ◽  
Pressure Plasma ◽  
High Prevalence ◽  
Blood Pressures

We are very interested to read the paper by Bannan et al. [1] about the effect of alcohol withdrawal on blood pressure, plasma renin activity, aldosterone, cortisol and dopamine β-hydroxylase. It has been known for several years that alcoholic patients admitted to hospital for detoxification have a high prevalence of hypertension [2]. Their blood pressures return to normal after alcohol withdrawal symptoms have abated and they remain normal if they continue to abstain. Patients who resume drinking sustain a rise in blood pressure to their former high levels.

Effect of alcohol withdrawal on blood pressure, plasma renin activity, aldosterone, cortisol and dopamine β-hydroxylase

1984 ◽  
Vol 66 (6) ◽  
pp. 659-663 ◽  
Author(s):  
L. T. Bannan ◽  
J. F. Potter ◽  
D. G. Beevers ◽  
J. B. Saunders ◽  
J. R. F. Walters ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Plasma Renin Activity ◽  
Alcohol Withdrawal ◽  
Diastolic Pressure ◽  
Urine Volume ◽  
Plasma Renin ◽  
Renin Activity ◽  
Withdrawal Symptoms ◽  
Urinary Volume ◽  
Blood Pressures

1. Sixty-five alcoholic patients admitted for detoxification had blood pressure, withdrawal symptoms, plasma cortisol (PC) and plasma aldosteron (PA) levels, plasma renin activity (PRA), and serum dopamin β-hydroxylase (DBH) levels measured on the first and fourth days after admission. 2. On the morning after admission blood pressure was elevated (>140/90) in 32 patients (49%) and was 160/95mmHg or more in 21 (32%). PRA was initially elevated in 41 patients, PA levels in 14, and 13 patients had raised PC levels. By the fourth day, blood pressure and bio-chemical measures had fallen significantly while urine volume and sodium output, low on admission, had increased significantly. On admission urinary metanephrine levels were raised in four out of the 31 patients who had them measured. 3. The height of both the systolic and diastolic blood pressures was significantly related to the severity of the alcohol. withdrawal symptoms. Of the biochemical parameters measured, PC level correlated with systolic but not diastolic pressure, and urinary volume was inversely correlated with the height of the diastolic pressure. No relationship was found between blood pressure and PRA or PA level. 4. The pressor effect of alcohol withdrawal could be due to sympathetic nervous system overactivity, or possibly to hypercortisolaemia. The first hypothesis seems more likely.

The Effect of Weight Reduction on Blood Pressure, Plasma Renin Activity, and Plasma Aldosterone Levels in Obese Patients

1981 ◽  
Vol 304 (16) ◽  
pp. 930-933 ◽  
Author(s):  
Michael L. Tuck ◽  
James Sowers ◽  
Leslie Dornfeld ◽  
Gary Kledzik ◽  
Morton Maxwell
Keyword(s):  
Blood Pressure ◽  
Plasma Renin Activity ◽  
Weight Reduction ◽  
Plasma Renin ◽  
Plasma Aldosterone ◽  
Renin Activity ◽  
Obese Patients ◽  
Pressure Plasma

Effect of Acute Volume Depletion on Blood Pressure, Plasma Renin Activity and Plasma Aldosterone Concentration in Hypertensive Subjects

1975 ◽  
Vol 39 (5) ◽  
pp. 545-549
Author(s):  
KENSHI KUMAMOTO ◽  
YOSHITAKA YAMAMOTO ◽  
TERUKAZU KAWASAKI ◽  
TERUO OMAE ◽  
KENJIRO TANAKA
Keyword(s):  
Blood Pressure ◽  
Plasma Renin Activity ◽  
Plasma Renin ◽  
Plasma Aldosterone ◽  
Renin Activity ◽  
Volume Depletion ◽  
Plasma Aldosterone Concentration ◽  
Pressure Plasma
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