scholarly journals Long-term in vivo depletion of functional CD4+ T lymphocytes from calves requires both thymectomy and anti-CD4 monoclonal antibody treatment

Immunology ◽  
2001 ◽  
Vol 102 (4) ◽  
pp. 426-433 ◽  
Author(s):  
R. A. Valdez ◽  
T. C. McGuire ◽  
W. C. Brown ◽  
W. C. Davis ◽  
D. P. Knowles
Keyword(s):  
Monoclonal Antibody ◽  
T Lymphocytes ◽  
Antibody Treatment ◽  
Monoclonal Antibody Treatment

scholarly journals The CD154/CD40 Interaction Required for Retrovirus-Induced Murine Immunodeficiency Syndrome Is Not Mediated by Upregulation of the CD80/CD86 Costimulatory Molecules

2002 ◽  
Vol 76 (24) ◽  
pp. 13106-13110 ◽  
Author(s):  
Kathy A. Green ◽  
W. James Cook ◽  
Arlene H. Sharpe ◽  
William R. Green
Keyword(s):  
Monoclonal Antibody ◽  
B Cells ◽  
Molecular Interactions ◽  
T And B Cells ◽  
Antibody Treatment ◽  
Monoclonal Antibody Treatment ◽  
Murine Aids ◽  
Cd40 Expression ◽  
Immunodeficiency Syndrome

ABSTRACT C57BL/6 (B6) mice infected with LP-BM5 retroviruses develop disease, including an immunodeficiency similar to AIDS. This disease, murine AIDS (MAIDS), is inhibited by in vivo anti-CD154 monoclonal antibody treatment. The similar levels of insusceptibility of CD40−/− and CD154−/− B6 mice indicate that CD154/CD40 molecular interactions are required for MAIDS. CD4+ T and B cells, respectively, provide the CD154 and CD40 expression needed for MAIDS induction. Here, the required CD154/CD40 interaction is shown to be independent of CD80 and CD86 expression: CD80/CD86−/− B6 mice develop MAIDS after LP-BM5 infection.

scholarly journals Long-term effects of anti-CD20 monoclonal antibody treatment of cryoglobulinaemic glomerulonephritis

2004 ◽  
Vol 19 (12) ◽  
pp. 3054-3061 ◽  
Author(s):  
D. Roccatello ◽  
S. Baldovino ◽  
D. Rossi ◽  
M. Mansouri ◽  
C. Naretto ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Long Term Effects ◽  
Antibody Treatment ◽  
Monoclonal Antibody Treatment ◽  
Anti Cd20

An investigation of allogeneic pregnancy in multiparous mice subjected to in vivo depletion of CD8 (Ly2)-positive lymphocytes by monoclonal antibody treatment

1988 ◽  
Vol 14 (3) ◽  
pp. 235-245 ◽  
Author(s):  
Pirkko Sulila ◽  
Rikard Holmdahl ◽  
Inga Hansson ◽  
Folke Bernadotte ◽  
Anita Mattsson ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Antibody Treatment ◽  
Monoclonal Antibody Treatment
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