Doppler assessment of the uterine and uteroplacental circulation in the second trimester in pregnancies at high risk for pre-eclampsia and/or intrauterine growth retardation: comparison and correlation between different Doppler parameters

1997 ◽  
Vol 9 (5) ◽  
pp. 330-338 ◽  
Author(s):  
P. Zimmermann ◽  
V. Eiriö ◽  
J. Koskinen ◽  
E. Kujansuu ◽  
T. Ranta
Author(s):  
M. R. Shaydullina ◽  
A. R. Shakirova ◽  
A. A. Zinatullina

Neonatal thyrotoxicosis is 1% of all cases of thyrotoxicosis in children and adolescents and it is mostly determined by the mother’s Graves’ disease. The most dangerous manifestations of neonatal thyrotoxicosis are intrauterine growth retardation, tachycardia, and heart rhythm disturbances. Timely diagnostics and beginning of treatment are of great importance due to the high risk of fatal cardiac disruption in the acute phase of the disease and its serious consequences for the body. The article presents a clinical case of a patient with neonatal thyrotoxicosis diagnosed only at the age of 1 month, despite the mother’s burdened anamnesis; it contains a plan for diagnostic search and tactics of child management.


2019 ◽  
Vol 13 (2) ◽  
pp. 103-110 ◽  
Author(s):  
E. N. Vasilyeva ◽  
L. I. Maltseva ◽  
T. G. Denisova ◽  
L. I. Gerasimova

Aim: to study the possibility of reducing the incidence of preeclampsia (PE) by giving vitamin D and calcium (Ca) to pregnant women with a high PE risk starting from the second trimester of pregnancy.Materials and methods. A total of 101 patients from the PE high risk group were examined on weeks 14–16 of pregnancy followed by treatment with vitamin D and Ca; then, the course of pregnancy and labor was analyzed. Serum 25-hydroxycholecalciferol, vitamin D binding protein, endothelin 1-38, and ionized Ca were determined using enzyme immunoassays.Results. In the examined women at high risk of PE, severe serum deficiency of vitamin D and Ca was detected. In patients treated with vitamin D and Ca, a two-fold decrease in the incidence of PE, a three-fold decrease in the incidence of intrauterine growth retardation syndrome, and a decrease in the number of urgent surgery-assisted deliveries were found.Conclusion. Therapy with vitamin D and Ca from the second trimester of pregnancy increases the availability of vitamin D, leads to a more favorable course of pregnancy, and prevents the development of severe forms and early onset of PE in patients at high risk.


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