The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis

Donat Kögel; Robert Schomburg; Tina Schürmann; Claus Reimertz; Hans-Georg König; Monika Poppe; Anne Eckert; Walter E. Müller; Jochen H. M. Prehn

doi:10.1046/j.1471-4159.2003.02000.x

The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2003.02000.x ◽

2003 ◽

Vol 87 (1) ◽

pp. 248-256 ◽

Cited By ~ 48

Author(s):

Donat Kögel ◽

Robert Schomburg ◽

Tina Schürmann ◽

Claus Reimertz ◽

Hans-Georg König ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Amyloid Precursor Protein ◽

Pc12 Cells ◽

Precursor Protein ◽

Induced Apoptosis

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The E693Δ Mutation in Amyloid Precursor Protein Increases Intracellular Accumulation of Amyloid β Oligomers and Causes Endoplasmic Reticulum Stress-Induced Apoptosis in Cultured Cells

American Journal Of Pathology ◽

10.2353/ajpath.2009.080480 ◽

2009 ◽

Vol 174 (3) ◽

pp. 957-969 ◽

Cited By ~ 78

Author(s):

Kazuchika Nishitsuji ◽

Takami Tomiyama ◽

Kenichi Ishibashi ◽

Kazuhiro Ito ◽

Rie Teraoka ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Amyloid Precursor Protein ◽

Cultured Cells ◽

Amyloid Β ◽

Precursor Protein ◽

Intracellular Accumulation ◽

Induced Apoptosis

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Enhanced Amyloidogenic Processing of Amyloid Precursor Protein and Cell Death Under Prolonged Endoplasmic Reticulum Stress in Brain Endothelial Cells

Molecular Neurobiology ◽

10.1007/s12035-014-8819-1 ◽

2014 ◽

Vol 51 (2) ◽

pp. 571-590 ◽

Cited By ~ 17

Author(s):

Ana I. Plácido ◽

Catarina R. Oliveira ◽

Paula I. Moreira ◽

Cláudia Maria F. Pereira

Keyword(s):

Endothelial Cells ◽

Endoplasmic Reticulum ◽

Cell Death ◽

Endoplasmic Reticulum Stress ◽

Amyloid Precursor Protein ◽

Precursor Protein ◽

Brain Endothelial Cells ◽

Amyloidogenic Processing

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Rosuvastatin protects PC12 cells from hypoxia/reoxygenation‑induced injury by inhibiting endoplasmic reticulum stress‑induced apoptosis

Experimental and Therapeutic Medicine ◽

10.3892/etm.2021.10623 ◽

2021 ◽

Vol 22 (4) ◽

Author(s):

Yu Gao ◽

Libo Li ◽

Jianbai Yu ◽

Zhanwei Zhang

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Pc12 Cells ◽

Induced Apoptosis ◽

Hypoxia Reoxygenation

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Amyloid precursor protein promotes endoplasmic reticulum stress-induced cell death via C/EBP homologous protein-mediated pathway

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2009.06067.x ◽

2009 ◽

Vol 109 (5) ◽

pp. 1324-1337 ◽

Cited By ~ 28

Author(s):

Keita Takahashi ◽

Tetsuhiro Niidome ◽

Akinori Akaike ◽

Takeshi Kihara ◽

Hachiro Sugimoto

Keyword(s):

Endoplasmic Reticulum ◽

Cell Death ◽

Endoplasmic Reticulum Stress ◽

Amyloid Precursor Protein ◽

Precursor Protein ◽

Homologous Protein

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The role of C-terminus of amyloid precursor protein under endoplasmic reticulum stress

Neuroscience Research ◽

10.1016/j.neures.2007.06.749 ◽

2007 ◽

Vol 58 ◽

pp. S175

Author(s):

Keita Takahashi ◽

Tetsuhiro Niidome ◽

Takeshi Kihara ◽

Hachiro Sugimoto

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Amyloid Precursor Protein ◽

Precursor Protein ◽

C Terminus

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Insulin-Like Growth Factor-1 Inhibits 6-Hydroxydopamine-Mediated Endoplasmic Reticulum Stress-Induced Apoptosis via Regulation of Heme Oxygenase-1 and Nrf2 Expression in PC12 Cells

International Journal of Neuroscience ◽

10.3109/00207454.2012.702821 ◽

2012 ◽

Vol 122 (11) ◽

pp. 641-649 ◽

Cited By ~ 20

Author(s):

Yumi Kim ◽

Endan Li ◽

Seungjoon Park

Keyword(s):

Endoplasmic Reticulum ◽

Growth Factor ◽

Endoplasmic Reticulum Stress ◽

Pc12 Cells ◽

Heme Oxygenase ◽

Heme Oxygenase 1 ◽

Insulin Like Growth Factor ◽

Induced Apoptosis ◽

6 Hydroxydopamine ◽

Nrf2 Expression

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Neuroprotective effect of polysaccharides from Gastrodia elata blume against corticosterone‑induced apoptosis in PC12 cells via inhibition of the endoplasmic reticulum stress‑mediated pathway

Molecular Medicine Reports ◽

10.3892/mmr.2017.7948 ◽

2017 ◽

Cited By ~ 3

Author(s):

Benhong Zhou ◽

Jun Tan ◽

Chan Zhang ◽

Yue Wu

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Pc12 Cells ◽

Neuroprotective Effect ◽

Gastrodia Elata ◽

Gastrodia Elata Blume ◽

Induced Apoptosis

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Isorhynchophylline Attenuates MPP+-Induced Apoptosis Through Endoplasmic Reticulum Stress- and Mitochondria-Dependent Pathways in PC12 Cells: Involvement of Antioxidant Activity

NeuroMolecular Medicine ◽

10.1007/s12017-017-8462-x ◽

2017 ◽

Vol 19 (4) ◽

pp. 480-492 ◽

Cited By ~ 12

Author(s):

Xiao-Ming Li ◽

Xiao-Jie Zhang ◽

Miao-Xian Dong

Keyword(s):

Antioxidant Activity ◽

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Pc12 Cells ◽

Induced Apoptosis

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Astragaloside IV ameliorates endoplasmic reticulum stress‑induced apoptosis of Aβ25‑35‑treated PC12 cells by inhibiting the p38�MAPK signaling pathway

Molecular Medicine Reports ◽

10.3892/mmr.2019.9855 ◽

2019 ◽

Author(s):

Yuhong Ma ◽

Li Xiong

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Signaling Pathway ◽

Pc12 Cells ◽

P38 Mapk ◽

Mapk Signaling ◽

Mapk Signaling Pathway ◽

Astragaloside Iv ◽

Induced Apoptosis

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Altered localization of amyloid precursor protein under endoplasmic reticulum stress

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2006.03.173 ◽

2006 ◽

Vol 344 (2) ◽

pp. 525-530 ◽

Cited By ~ 40

Author(s):

Takashi Kudo ◽

Masayo Okumura ◽

Kazunori Imaizumi ◽

Wataru Araki ◽

Takashi Morihara ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Amyloid Precursor Protein ◽

Precursor Protein

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