Does LCIS or ALH Without Other High-Risk Lesions Diagnosed on Core Biopsy Require Surgical Excision?

2003 ◽  
Vol 9 (1) ◽  
pp. 1-3 ◽  
Author(s):  
D. David Dershaw
2021 ◽  
Vol 216 (3) ◽  
pp. 622-632
Author(s):  
Aya Y. Michaels ◽  
Paula S. Ginter ◽  
Katerina Dodelzon ◽  
Matthew R. Naunheim ◽  
Genevieve N. Abbey

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Eka Rozentsvayg ◽  
Kristen Carver ◽  
Sunita Borkar ◽  
Melvy Mathew ◽  
Sean Enis ◽  
...  

Our goal was to assess the value of surgical excision of benign papillomas of the breast diagnosed on percutaneous core biopsy by determining the frequency of upgrade to malignancies and high risk lesions on a final surgical pathology. We reviewed 67 patients who had biopsies yielding benign papilloma and underwent subsequent surgical excision. Surgical pathology of the excised lesions was compared with initial core biopsy pathology results. 54 patients had concordant benign core and excisional pathology. Cancer (ductal carcinoma in situ and invasive ductal carcinoma) was diagnosed in five (7%) patients. Surgery revealed high-risk lesions in 8 (12%) patients, including atypical ductal hyperplasia, atypical lobular hyperplasia, and lobular carcinoma in situ. Cancer and high risk lesions accounted for 13 (19%) upstaging events from benign papilloma diagnosis. Our data suggests that surgical excision is warranted with core pathology of benign papilloma.


2012 ◽  
Vol 82 (3) ◽  
pp. 168-172 ◽  
Author(s):  
Qinghui Lu ◽  
Ern Yu Tan ◽  
Bernard Ho ◽  
Juliana J. C. Chen ◽  
Patrick M. Y. Chan

2018 ◽  
Vol 6 (1) ◽  
pp. 35-37
Author(s):  
Uwe Wollina ◽  
Dana Langner ◽  
Jacqueline Schönlebe ◽  
Katlein França ◽  
Torello Lotti ◽  
...  

Dermatofibrosarcoma protuberans (DFSP) is rare mesenchymal neoplasia with a high risk of local recurrence but a low risk of metastatic spread. Tumor cells express CD34 and show a characteristic translocation t(17;22)(q22;q13). We analysed the documented cases at the Department of Dermatology and Allergology between 08/2001 and 08/2017. The diagnosis had been confirmed by histology and immunohistology in all cases. We identified four adults and a pediatric patient with DFSP. All patients were treated by wide surgical excision and controlled by three-dimensional histologic margin control. We observed no recurrence and no metastatic spread. We discuss prognostic factors and emerging treatments.


Breast Cancer ◽  
2019 ◽  
Vol 27 (3) ◽  
pp. 405-414
Author(s):  
Satoko Okamoto ◽  
Shu-Tian Chen ◽  
James D. Covelli ◽  
Wendy B. DeMartini ◽  
Bruce L. Daniel ◽  
...  

2019 ◽  
Vol 475 (6) ◽  
pp. 701-707 ◽  
Author(s):  
Christine MacColl ◽  
Amir Salehi ◽  
Sameer Parpia ◽  
Nicole Hodgson ◽  
Milita Ramonas ◽  
...  

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