Demystifying Which High-risk Lesions Truly Require Surgical Excision—A Call to Action

2021 ◽  
Vol 3 (5) ◽  
pp. 581-582
Author(s):  
Habib Rahbar
Keyword(s):  
High Risk ◽  
Surgical Excision ◽  
Call To Action

scholarly journals Dermatofibrosarcoma Protuberans: Retrospective Single Center Analysis Over 16 Years

2018 ◽  
Vol 6 (1) ◽  
pp. 35-37
Author(s):  
Uwe Wollina ◽  
Dana Langner ◽  
Jacqueline Schönlebe ◽  
Katlein França ◽  
Torello Lotti ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
High Risk ◽  
Local Recurrence ◽  
Three Dimensional ◽  
Dermatofibrosarcoma Protuberans ◽  
Surgical Excision ◽  
Metastatic Spread ◽  
Single Center ◽  
Emerging Treatments ◽  
Margin Control

Dermatofibrosarcoma protuberans (DFSP) is rare mesenchymal neoplasia with a high risk of local recurrence but a low risk of metastatic spread. Tumor cells express CD34 and show a characteristic translocation t(17;22)(q22;q13). We analysed the documented cases at the Department of Dermatology and Allergology between 08/2001 and 08/2017. The diagnosis had been confirmed by histology and immunohistology in all cases. We identified four adults and a pediatric patient with DFSP. All patients were treated by wide surgical excision and controlled by three-dimensional histologic margin control. We observed no recurrence and no metastatic spread. We discuss prognostic factors and emerging treatments.

scholarly journals Fatigue Risk Management in High-Risk Environments: A Call to Action

2018 ◽  
Vol 22 (sup1) ◽  
pp. 1-2 ◽  
Author(s):  
Deborah A. P. Hersman ◽  
Emily A. Whitcomb
Keyword(s):  
Risk Management ◽  
High Risk ◽  
Call To Action ◽  
Risk Environments ◽  
High Risk Environments

High-Risk Lesions Detected by MRI-Guided Core Biopsy: Upgrade Rates at Surgical Excision and Implications for Management

2021 ◽  
Vol 216 (3) ◽  
pp. 622-632
Author(s):  
Aya Y. Michaels ◽  
Paula S. Ginter ◽  
Katerina Dodelzon ◽  
Matthew R. Naunheim ◽  
Genevieve N. Abbey
Keyword(s):  
High Risk ◽  
Core Biopsy ◽  
Surgical Excision ◽  
Mri Guided

High-risk lesions diagnosed at MRI-guided vacuum-assisted breast biopsy: imaging characteristics, outcome of surgical excision or imaging follow-up

Breast Cancer ◽  
2019 ◽  
Vol 27 (3) ◽  
pp. 405-414
Author(s):  
Satoko Okamoto ◽  
Shu-Tian Chen ◽  
James D. Covelli ◽  
Wendy B. DeMartini ◽  
Bruce L. Daniel ◽  
...  
Keyword(s):  
High Risk ◽  
Breast Biopsy ◽  
Surgical Excision ◽  
Imaging Characteristics ◽  
Mri Guided

scholarly journals Embryonal carcinoma of an intraabdominal testicular tumor on an undescended testicle: a case report

2020 ◽  
Author(s):  
Mihai Domnutiu Suciu ◽  
Nucu Alexandru Marica ◽  
Traian Oniu ◽  
Andrei Ionut Tomuta ◽  
Radu Badea
Keyword(s):  
High Risk ◽  
Embryonal Carcinoma ◽  
Testicular Tumor ◽  
Surgical Excision ◽  
Testicular Tumors ◽  
Retroperitoneal Lymphadenectomy ◽  
Left Testicle ◽  
Lymphnode Metastasis ◽  
Risk Of Malignancy ◽  
Histological Result

Cryptorchidism, as a singular pathology or associated with other dysgenesis syndromes, is one of the main factors of risk for the development of the testicular tumors. Although there are a great number of cases of undescended testicles that are diagnosed and treated during the first 6-12 months of life, there are rare cases of adults who are undiagnosed and untreated from this anomaly, which can present a high risk of malignancy . In this study we present the case of a 36-year-old patient, diagnosed at puberty with left cryptorchidism, untreated, who also hadevidenced a large intraabdominal tumoral mass associated with it. The tumoral mass had its origin in the undescended left testicle. Surgical excision of the tumor and retroperitoneal lymphadenectomy was performed. The histological result revealed embryonal carcinoma, without lymphnode metastasis. Adult patients with untreated cryptorchidism should be thoroughly investigated, as they have a high risk of developing testicular cancer.

scholarly journals High-Risk Breast Lesions: A Machine Learning Model to Predict Pathologic Upgrade and Reduce Unnecessary Surgical Excision

Radiology ◽  
2018 ◽  
Vol 286 (3) ◽  
pp. 810-818 ◽  
Author(s):  
Manisha Bahl ◽  
Regina Barzilay ◽  
Adam B. Yedidia ◽  
Nicholas J. Locascio ◽  
Lili Yu ◽  
...  
Keyword(s):  
Machine Learning ◽  
High Risk ◽  
Surgical Excision ◽  
Learning Model ◽  
Breast Lesions ◽  
Machine Learning Model ◽  
High Risk Breast

scholarly journals Surgical Excision of Benign Papillomas Diagnosed with Core Biopsy: A Community Hospital Approach

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Eka Rozentsvayg ◽  
Kristen Carver ◽  
Sunita Borkar ◽  
Melvy Mathew ◽  
Sean Enis ◽  
...  
Keyword(s):  
High Risk ◽  
Core Biopsy ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Lobular Carcinoma ◽  
Surgical Excision ◽  
Surgical Pathology ◽  
Ductal Hyperplasia ◽  
Benign Papilloma

Our goal was to assess the value of surgical excision of benign papillomas of the breast diagnosed on percutaneous core biopsy by determining the frequency of upgrade to malignancies and high risk lesions on a final surgical pathology. We reviewed 67 patients who had biopsies yielding benign papilloma and underwent subsequent surgical excision. Surgical pathology of the excised lesions was compared with initial core biopsy pathology results. 54 patients had concordant benign core and excisional pathology. Cancer (ductal carcinoma in situ and invasive ductal carcinoma) was diagnosed in five (7%) patients. Surgery revealed high-risk lesions in 8 (12%) patients, including atypical ductal hyperplasia, atypical lobular hyperplasia, and lobular carcinoma in situ. Cancer and high risk lesions accounted for 13 (19%) upstaging events from benign papilloma diagnosis. Our data suggests that surgical excision is warranted with core pathology of benign papilloma.

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