Postoperative adjuvant therapy in early invasive cervical cancer patients with histopathologic high-risk factors

2001 ◽  
Vol 11 (6) ◽  
pp. 475-482 ◽  
Author(s):  
T. K. Park ◽  
S. N. Kim ◽  
J. Y. Kwon ◽  
H. J. Mo
Keyword(s):  
Risk Factors ◽  
Cervical Cancer ◽  
High Risk ◽  
Adjuvant Therapy ◽  
Cancer Patients ◽  
Invasive Cervical Cancer ◽  
Postoperative Adjuvant Therapy ◽  
High Risk Factors

scholarly journals Concurrent chemotherapy and radiotherapy in invasive cervical cancer patients with high risk factors

2000 ◽  
Vol 15 (4) ◽  
pp. 436 ◽  
Author(s):  
Tchan Kyu Park ◽  
Soo Nyung Kim ◽  
Sang Wun Kim ◽  
Gwi Eon Kim ◽  
Chang Ok Suh
Keyword(s):  
Risk Factors ◽  
Cervical Cancer ◽  
High Risk ◽  
Cancer Patients ◽  
Invasive Cervical Cancer ◽  
Concurrent Chemotherapy ◽  
High Risk Factors

scholarly journals Progress of adjuvant therapy after radical resection of early cervical cancer

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Zhen Zhang
Keyword(s):  
Risk Factors ◽  
Cervical Cancer ◽  
High Risk ◽  
Adjuvant Therapy ◽  
Cancer Patients ◽  
Research Progress ◽  
External Irradiation ◽  
High Risk Factors ◽  
First Choice ◽  
Early Cervical Cancer

Radical surgery is the first choice for the treatment of early cervical cancer. Patients need radiotherapy and chemotherapy according to the risk factors.concurrent chemoradiotherapy with cisplatin is recommended according to NCCN recommended guidelines for the treatment of cervical cancer, with any post-operative high risk factors (lymph node metastasis, positive vaginal margin, and para-uterine infiltration). for cervical cancer patients without high risk factors but with moderate risk factors that meet Sedlis criteria, it is recommended to supplement post-operative pelvic external irradiation ± with concurrent chemotherapy with cisplatin.However, these adjuvant treatments can cause radioactive cystitis and proctitis, even vesicovaginal fistula, rectovaginal fistula, long or irreversible adverse reactions, affecting ovarian function in young patients who retain the ovary, which can lead to a decline in the quality of life of patients. These problems make it a hot topic whether chemotherapy can be used in postoperative adjuvant therapy of cervical cancer patients. This article reviews the research progress of adjuvant therapy for early cervical cancer.

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