scholarly journals From particle physics: To medtech and biomedical research

2018 ◽  
Vol 49 (5-6) ◽  
pp. 35-38
Author(s):  
Manuela Cirilli

Physics phenomena underpin many techniques and technologies that are used for both diagnosis and treatment of a variety of diseases. This is the case for radiotherapy, Magnetic Resonance Imaging (MRI), and Positron Emission Tomography (PET) that are based on our knowledge, respectively, of how particles interact with matter, of how atomic nuclei behave in oscillating magnetic fields, and of how positron decay.

2012 ◽  
Vol 25 (2) ◽  
pp. 177-181 ◽  
Author(s):  
Helen F.K. Chiu ◽  
Henry Brodaty

Impressive developments in the biomarker diagnosis of Alzheimer's disease (AD and pre-symptomatic states, using cerebrospinal fluid (CSF), positron emission tomography (PET), magnetic resonance imaging (MRI), and proteomics, have been at the forefront of research in the last decade. With the publication of the criteria of Dubois et al. (2007) and the revised National Institute on Aging and Alzheimer's Association (NIA–AA) criteria for the diagnosis of AD (Jack et al., 2011), this has further ignited the interest and enthusiasm for researchers and clinicians in the field. In some of the major conferences on dementia in recent years, the topic of the biomarker-driven diagnosis of AD has dominated the research agenda. But many questions arise as to how this research will translate into practice. Here, we would like to put forward our arguments against a biomarker-driven diagnosis of AD, and we would caution that very early diagnosis of AD may not result in better care of the subjects.


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