scholarly journals The outcome of expandable titanium mesh implants for the treatment of multi-level vertebral compression fractures caused by multiple myeloma

SICOT-J ◽  
2021 ◽  
Vol 7 ◽  
pp. 28
Author(s):  
Surya Gandham ◽  
Abdurrahman Islim ◽  
Saud Alhamad ◽  
Sathya Thambiraj

Background: Painful vertebral compression fractures (VCFs) in myeloma patients severely reduce quality of life. Currently, the International Myeloma Working Group (IMWG) and National Institute of Clinical Excellence NICE advocate the use of either balloon kyphoplasty or vertebroplasty in the management of these fractures. Methods: All patients with VCFs and myeloma who adhered to the IMWG indications for vertebral augmentation were treated with the Osseofix® implant. Visual analogue scores (VAS) and Oswestry disability index (ODI) were taken preoperatively and at least one year following surgery. Cobb angle and implant migration were measured on lateral standing radiographs. Results: Sixteen patients (average age 62, SD = 11.6) consisting of 82 levels (range 3–8) were stabilised with no perioperative complications or revisions at one year. There was an improvement in patient-reported outcomes with the median preoperative VAS of 8.6 (IQR 7.3–10.0) reducing to 3 (IQR 1.0–4.0) after one year (P < 0.001) whilst an average improvement of 31.4 (SD = 19.6) points in the ODI scores was reported (P < 0.001). There was no significant collapse or implant failure at one year with a greater improvement in the VAS/ODI score, when more implants were used (P = 0.049 and 0.008, respectively). The average length of stay was 2.2 days (SD = 1.7). Conclusion: The use of the Osseofix® implant in VCFs caused by multiple myeloma has shown a statistically significant improvement in both pain and outcome scores. There were no complications or significant radiological deterioration of spinal alignment over the course of a year.

2015 ◽  
Vol 15 (3) ◽  
pp. S61
Author(s):  
Charalampia Kyriakou ◽  
Anand Patel ◽  
Shivan Jassim ◽  
Adam Benton ◽  
Susanne Selvadurai ◽  
...  

10.29007/mkj3 ◽  
2020 ◽  
Author(s):  
John Keggi ◽  
Jeffrey Lawrence ◽  
Amber Randall ◽  
Jeffrey DeClaire ◽  
Corey Ponder ◽  
...  

This study reports on the one-year clinical results and patient reported outcomes (PROMs) associated with a new ‘predictive balance’ tibia-cut first total knee arthroplasty (TKA) technique that uses a robotic ligament tensioner. PROMs are compared to registry data and historical results in the literature.Five hundred and thirty-three patients were prospectively enrolled and underwent robotic TKA (mean age: 67.7±8.4; females: 320; BMI: 31.2±4.9). Pre-op, three, six and 12-month WOMAC, UCLA activity scale, and HSS-Patient satisfaction assessments were completed by 533, 352, 314, and 256 patients, respectively, and compared to WOMAC registry data from the Shared Ortech Aggregated Repository (SOAR) and to historical satisfaction reports in the literature.Despite having equivalent baseline PROM scores, predictive balance patients had significantly higher WOMAC scores at all post-operative timepoints (p&lt;0.001) and higher UCLA activity scale scores at 3M and 6M (p&lt;0.013). Overall patient satisfaction in the predictive balance cohort was 91.2%, 92.4%, and 96.5% at 3M, 6M and 1YR, respectively. Average length of stay was 1.6 days (±0.8). Surgical complications in this cohort were typical of TKA.Limitations to this study include the lack of a closely matched control group. Nonetheless, first year results are promising with improved objective measures compared to large registry databases and recently reported patient satisfaction measures.


2015 ◽  
Vol 2;18 (2;3) ◽  
pp. E187-E194
Author(s):  
Lin Nie

Background: Percutaneous vertebroplasty is a widely used vertebral augmentation procedure for treating osteoporotic vertebral compression fractures (OVCFs). But high cement leakage rate caused by a low-viscosity cement and high injection pressure has limited its general use. Balloon kyphoplasty (BKP) and high-viscosity cement vertebroplasty (HVCV) are 2 modifications of vertebroplasty designed to decrease cement leakage. Objective: To assess the safety and efficacy of HVCV compared with BKP. Study Design: A prospective cohort study. Setting: Department of Spine Surgery, an affiliated hospital of a medical university. Method: One hundred seven patients suffering from painful OVCFs were randomly assigned into HVCV or BKP groups. Visual Analog Scale (VAS), Oswestry Disability Index (ODI), cement leakage, and vertebral height restoration were evaluated. All occurring complications and injected cement volumes were recorded. The follow-up time was one year. Results: VAS and ODI scores improved in both groups, and did not differ significantly between the 2 groups. More cement was used in the BKP group than in HVCV group (4.22 vs. 3.31 mL, P < 0.0001). The incidence of cement leakage in the HVCV group was lower than that of the BKP group (13.24% vs 30.56%, P < 0.05). No symptomatic cement leakages occurred in the HVCV group. In the BKP group, one patient experienced discogenic back pain related to a disc leak, and another patient had asymptomatic cement emboli in the lung related to venous leakage. The mean compression rate before the procedure was 29.98% in the HVCV group and 28.67% in the BKP group (P = 0.94). The vertebral height was improved significantly and maintained at one-year follow-up in both groups. BKP was more effective in vertebral height restoration than HVCV (44.87% vs. 23.93%, P < 0.0001). There was one case of a new adjacent vertebral fracture in the HVCV group (2%), and 4 cases of new nonadjacent vertebral fractures in the BKP group (7.84%) (P = 0.18). Limitations: A single-center and relatively small-sample size study. Conclusion: HVCV and BKP are safe and effective in improving quality of life and relieving pain. HVCV has a lower cement leakage rate, whereas BKP is more effective in vertebral height restoration. Subsequent fractures are not different between the 2 groups. Key words: Vertebral compression fracture, spine, osteoporosis, cement augmentation, balloon kyphoplasty, vertebroplasty, cement leakage


2018 ◽  
Vol 07 (03) ◽  
Author(s):  
Cornelis Wilhelmus Jacobus van Tilburg ◽  
Johannes George Groeneweg ◽  
Dirk Leendert Stronks ◽  
Frank Johannes Petrus Maria Huygen

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