Compliance With and Timing of Prophylactic Antibiotic Administration and Risk of Peristomal Wound Infection After Percutaneous Endoscopic Gastrostomy

2016 ◽  
Vol 151 (1) ◽  
pp. 200
Author(s):  
Alisa Likhitsup ◽  
Devika Kapuria ◽  
Wendell K. Clarkston
1989 ◽  
Vol 3 (1) ◽  
pp. 26-28
Author(s):  
Ronald J. Bridges ◽  
Lloyd R. Sutherland ◽  
Sydney Bass ◽  
Lorne M. Price

Sixty-five patients who had endoscopic placement of a feeding tube between April 1984 and November 1987, were reviewed. Mean follow-up was 245 days (range one to 1391 days). The most common indication for gastrostomy insertion was a neurologic disorder (83%) Prophylactic antibiotic (cefoxitin) was given to 55% of patients (86% from one hospital). Minor complications (superficial wound infection, tube malfunction, ileus or localized abdominal pain) were seen in 55% of patients. Superficial wound infection, defined as local erythema and/or purulent discharge. was the most common complication ( 33%). No significant difference was found in the incidence of superficial wound infection between the group receiving prophylactic antibiotic and those who did not Major complications (gastric bleeding, aspiration, respiratory depression or abdominal abscess) occurred in 14% of patients The overall 30 day mortality was 23%. In 60% the cause of death was secondary to the underlying illness. No deaths occurred due to prolonged use of the feeding tube. Five patients (8%) regained the ability to eat resulting in tube removal. The authors’ experience suggests that percutaneous endoscopic gastrostomy (PEG). perhaps because of the patient population b associated with significant morbidity and mortality. Prophylactic antibiotics did not alter the incidence of wound infection associated with PEG However. this may be related to the use of a prophylactic antibiotic (cefoxttin) that has relatively poor coverage forStaphylococcus aureus, the most common organism cultured. Careful consideration must be given to patient selection prior to undertaking the procedure.


2021 ◽  
pp. 089686082110576
Author(s):  
Caroline Kempf ◽  
Johannes Holle ◽  
Susanne Berns ◽  
Stephan Henning ◽  
Philip Bufler ◽  
...  

Background: Peritoneal dialysis (PD) is the preferred dialysis modality for paediatric patients with end-stage kidney disease. Frequently, malnutrition is encountered. Percutaneous endoscopic gastrostomy (PEG) is the preferred mode of feeding because of its minimal invasive mode of placement and easy handling in daily life. However, reports of a high risk for early post-interventional peritonitis hampered this procedure during PD and controlled studies on the benefit of peri-interventional management to prevent peritonitis are lacking. Here, we report the safety profile of PEG insertion among a cohort of children on PD by using a prophylactic antibiotic and antifungal regimen as well as modification of the PD programme. Methods: We performed a single-centre analysis of paediatric PD patients receiving PEG placement between 2015 and 2020. Demographic data, peri-interventional prophylactic antibiotic and antifungal treatment as well as modification of the PD programme were gathered and the incidence of peritonitis within a period of 28 days after PEG was calculated. Results: Eight PD patients (median weight 6.7 kg) received PEG insertion. Antibiotic and antifungal prophylaxis were prescribed for median time of 4.0 and 5.0 days, respectively. After individual reduction of PD intensity, all patients continued their regular PD programme after a median of 6 days. One patient developed peritonitis within 24 h after PEG insertion and simultaneous surgery for hydrocele. Conclusions: Applying an antibiotic and antifungal prophylactic regime as well as an adapted PD programme may reduce the risk for peritonitis in paediatric PD patients who receive PEG procedure.


2004 ◽  
Vol 59 (5) ◽  
pp. P160
Author(s):  
Han-Hyo Lee ◽  
Ki-Nam Shim ◽  
Jung-Mi Kwon ◽  
Jun-Sik Nam ◽  
Moon Sun Yeom ◽  
...  

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