Pathologic Aspects of Inflammatory Breast Carcinoma: Part 1. Histomorphology and Differential Diagnosis

Abstract Nephrogenic systemic fibrosis, previously known as nephrogenic fibrosing dermopathy, is a newly recognized systemic fibrosing disorder primarily affecting patients with chronic renal failure. Patients with skin involvement often develop papules and plaques with peau d'orange surface changes. The lower extremities and trunk are most commonly affected. The most important histologic differential diagnosis is with scleromyxedema. To our knowledge, we report the first case of nephrogenic systemic fibrosis involving the breasts of a 61-year-old woman with end-stage renal disease, clinically mimicking inflammatory breast carcinoma. We propose that nephrogenic systemic fibrosis be considered in the differential diagnosis as a rare possibility when cutaneous changes in the breast suggest inflammatory breast carcinoma in a patient with renal failure.

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Delayed presentation of inflammatory breast carcinoma during the COVID-19 pandemic

European Surgery ◽

10.1007/s10353-021-00726-8 ◽

2021 ◽

Author(s):

Daniele Bernardi ◽

Emanuele Asti ◽

Giulia Bonavina ◽

Alberto Luporini ◽

Claudio Clemente ◽

...

Keyword(s):

Breast Carcinoma ◽

Delayed Presentation ◽

Inflammatory Breast Carcinoma

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Wnt (canonical and non canonical) pathways in breast carcinoma with extensive vascular invasion and inflammatory breast carcinoma

Pathology - Research and Practice ◽

10.1016/j.prp.2021.153347 ◽

2021 ◽

Vol 219 ◽

pp. 153347

Author(s):

A. Remo ◽

S. Sina ◽

S. Barbi ◽

I. Simeone ◽

J. Insolda ◽

...

Keyword(s):

Breast Carcinoma ◽

Vascular Invasion ◽

Inflammatory Breast Carcinoma ◽

Canonical Pathways

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Case Report and Literature Review of Nodular Hidradenoma, a Rare Adnexal Tumor That Mimics Breast Carcinoma, in a 20-Year-Old Woman

Laboratory Medicine ◽

10.1093/labmed/lmy084 ◽

2019 ◽

Vol 50 (3) ◽

pp. 320-325

Author(s):

Vanya Jaitly ◽

Richard Jahan-Tigh ◽

Tatiana Belousova ◽

Hui Zhu ◽

Robert Brown ◽

...

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Breast Carcinoma ◽

Literature Review ◽

Sweat Glands ◽

Rare Presentation ◽

Adnexal Tumor ◽

Nodular Hidradenoma ◽

Growing Mass ◽

Uncommon Tumor

Abstract Nodular hidradenoma is an uncommon cutaneous adnexal tumor arising from sweat glands. In the skin, it usually presents as a solitary dermal nodule; excision is curative in most cases. In rare instances, it may present as a breast mass and can mimic breast carcinoma clinically and radiologically, causing diagnostic dilemmas for the treating physician and pathologist. Herein, we discuss a case of nodular hidradenoma in a 20-year-old Hispanic woman as a rapidly growing mass in the breast that mimicked breast carcinoma. We discuss the rare presentation of this uncommon tumor and the differential diagnosis of this entity, as well as the results of our literature review on the topic.

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