Botulinum toxoid in the management of gustatory sweating (Frey’s syndrome) after superficial parotidectomy

1999 ◽  
Vol 52 (3) ◽  
pp. 230-231 ◽  
Author(s):  
J.F. Birch ◽  
S.K. Varma ◽  
A.A. Narula
1997 ◽  
Vol 111 (9) ◽  
pp. 839-844 ◽  
Author(s):  
A. Bjerkhoel ◽  
O. Trobbe

AbstractFrey's syndrome, i.e. gustatory sweating on the cheek, is a fairly common embarrassment after parotid gland surgery. New surgical techniques have been proposed to avoid this complication, but are not widely in use. Hence, there is need for treatment of Frey's syndrome. All surgical and topical treatments have drawbacks. This study was set up in order to evaluate a recently described treatment. One hundred and two patients were interviewed after parotidectomy. Thirty-one of them had noticed gustatory sweating and 15 patients underwent Minor's starch iodine test before, and after, treatment with intracutaneous injections of botulinum toxin A (Botox®, Allergan Inc., USA). Thirteen of the patients did not experience any gustatory sweating at follow-up (one to 13 months). Minor's starch test showed total disappearance of gustatory sweating in 12 of the 15 treated patients. The only side effect was a discreet, transitory affection of the orbicularis oris muscle in one patient. As this treatment is minimally invasive it could be an attractive treatment for Frey's syndrome if the effect is maintained. Complaints of local hypoaesthesia and pain were also common after parotid surgery.


Head & Neck ◽  
2003 ◽  
Vol 25 (8) ◽  
pp. 624-628 ◽  
Author(s):  
Andr� Eckardt ◽  
Christian Kuettner

1990 ◽  
Vol 72 (6) ◽  
pp. 955-958 ◽  
Author(s):  
Giuseppe De Benedittis

✓ Two cases of auriculotemporal nerve syndrome (Frey's syndrome) presenting as trigeminal tic douloureux are reported. This condition, characterized by gustatory sweating and facial hyperemia, is occasionally associated with pain, which is usually described as aching or burning, and long-lasting. In these two cases, however, a tantalizing gustatory pain occurred in excruciating brief paroxysms. The pathophysiology of the syndrome, with particular reference to pain, and possible treatment modalities are discussed.


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