scholarly journals Does the PillCam SB3 capsule endoscopy system improve image reading efficiency irrespective of experience? A pilot study

2018 ◽  
Vol 06 (06) ◽  
pp. E669-E675 ◽  
Author(s):  
Teppei Omori ◽  
Toshifumi Hara ◽  
Sachiyo Sakasai ◽  
Harutaka Kambayashi ◽  
Shun Murasugi ◽  
...  
Keyword(s):  
Small Intestine ◽  
Capsule Endoscopy ◽  
Reading Time ◽  
Diagnostic Efficiency ◽  
Hospital Data ◽  
Reading Efficiency ◽  
Significant Difference ◽  
Intermediate Readers ◽  
Time Burden ◽  
Small Intestinal

Abstract Background and study aims The aim of this study was tp compare the diagnostic efficiency of the PillCam SB3 capsule endoscopy (CE) system with the older system, PillCam SB2, taking into consideration the experience of the image reader. Patients and methods Small intestinal CE was conducted on 64 patients around May 2014 when the SB3 was introduced in our hospital. Data obtained from 20 patients (SB2: 10 and SB3: 10) based on transit time were assessed by junior (experience: 20 images), intermediate (> 50), and expert readers (> 600). Results Reading time with the CE down to the end of the small intestine was shorter in the SB3 group for each reader (SB2 vs. SB3: junior, 40.2 ± 10.1 vs. 23.7 ± 6.7 [P = 0.0009]; intermediate, 21.4 ± 4.9 vs. 10.3 ± 2.9 [P = 0.0003]; expert, 23.2 ± 5.6 vs. 11.1 ± 2.9 min [P = 0.0002]). Interpretation agreement rates between the findings by junior and intermediate readers and those by the expert reader were 84.6 % and 92.3 %, respectively. For the junior reader, rates of agreement using the SB2 and SB3 systems with those by the expert reader were 85.7 % and 83.3 %, respectively; no significant difference was noted between the two systems. Similarly, for the intermediate reader, the respective agreement rates using the SB2 and SB3 systems were 85.7 % and 100 %, respectively. Conclusions The PillCam SB3 reduces the time burden on readers irrespective of their experience.

Su1211 The Utility of Small Intestine Capsule Endoscopy and Balloon-Assisted Enteroscopy in the Diagnosis of Small Intestinal Tumors

2017 ◽  
Vol 85 (5) ◽  
pp. AB316
Author(s):  
Ryoichi Sawada ◽  
Ryosuke Miyazaki ◽  
Ayako Ishii ◽  
Yusuke Nagata ◽  
Makio Ogawa ◽  
...  
Keyword(s):  
Small Intestine ◽  
Capsule Endoscopy ◽  
Intestinal Tumors ◽  
Small Intestinal

Su1232 The Utility of Small Intestine Capsule Endoscopy and Balloon-Assisted Enteroscopy for Diagnosis of Small Intestinal Tumor

2016 ◽  
Vol 83 (5) ◽  
pp. AB321
Author(s):  
Yusuke Nagata ◽  
Ryoichi Sawada ◽  
Takashi Nishimura ◽  
Kanae Tsutsui ◽  
Hiroki Saijo ◽  
...  
Keyword(s):  
Small Intestine ◽  
Capsule Endoscopy ◽  
Intestinal Tumor ◽  
Small Intestinal ◽  
Small Intestinal Tumor

scholarly journals Evaluation of Performance in Colon Capsule Endoscopy Reading by Endoscopy Nurses

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Yukiko Handa ◽  
Konosuke Nakaji ◽  
Kayo Hyogo ◽  
Makiko Kawakami ◽  
Tomomi Yamamoto ◽  
...  
Keyword(s):  
Capsule Endoscopy ◽  
Detection Rate ◽  
Reading Time ◽  
Diagnostic Yield ◽  
Detection Rates ◽  
Colon Capsule Endoscopy ◽  
Significant Difference ◽  
Novice Nurses ◽  
Colon Capsule ◽  
Clinically Significant

Background. Although there are papers reporting on the accuracy of colon capsule endoscopy (CCE) compared with colonoscopy (CS), there are few reports on the detection rates of significant lesions by endoscopy nurses. We previously reported no significant difference in the detection rates for small bowel capsule endoscopy (SBCE) images among two well-trained physicians and one expert nurse. Objective. To evaluate the reading time and detection rate of the significant lesions of CCE images among novice and trained expert endoscopy nurses and novice physicians. Methods. CCE videos of 20 consecutive patients who performed both CCE and CS with clinically significant localized lesions were selected. Two trained expert endoscopy nurses, untrained two novice physicians, and novice three endoscopy nurses reviewed CCE videos. The detection rate of the lesions and reading time were compared among the three groups and were evaluated by comparison between the first and the second 10 videos. Results. The median reading time was the shortest (19 min) in the trained expert endoscopy nurses and the longest (45 min) in the novice nurses. The number of thumbnails tended to be more in the trained expert endoscopy nurses in the first 10-video reading. Although the detection rates of small polyps (<5 mm) were significantly lower (46.5%, p = 0.025 ) in the novice nurses compared to the others, they were improved (35.2% to 63.5%, p = 0.015 ) in the second 10 videos. The detection rates of tumor lesions by either one of two trained expert endoscopy nurses were higher compared to those by each novice physician. Conclusions. The trained expert endoscopy nurses for CCE reading can reduce physician's time and improve the diagnostic yield.

Effect of Lunasin Extract on Histopathology of Mice Induced with Azoxymethane and Dextran Sodium Sulfate: Focus on Small Intestine Changes

2018 ◽  
Vol 24 (8) ◽  
pp. 6117-6124
Author(s):  
Euginia Christa ◽  
Kusmardi
Keyword(s):  
Small Intestine ◽  
Sodium Sulfate ◽  
Goblet Cells ◽  
Dextran Sodium Sulfate ◽  
Intestinal Tissue ◽  
Small Intestine Cancer ◽  
Significant Difference ◽  
Small Intestinal ◽  
Diet And Lifestyle ◽  
Hematoxylin Eosin

Within the last decade, incidence of small bowel cancer has increased by more than fourfold. This number is predicted to steadily rise due to shift in diet and lifestyle. The primary and only definite therapy for small intestine cancer is radical segmental resection, which carries side effects and risks during and after surgery. Current chemotherapy and neoadjuvant therapy do not exert significant result. Lunasin, a novel peptide originated from soybean, is believed to promote cellular health epigenetically and reduce inflammation. There is possibility for lunasin extract to emerge as a new and effective adjuvant therapy for small intestine malignancies. A total of 20 Balb/c mice were divided into four groups. All mice were induced with azoxymethane and dextran sodium sulfate. For the next six weeks, each group was given different concentration of lunasin extract. After eight weeks, the mice were sacrificed. The small intestinal tissue was harvested and stained using hematoxylin-eosin. The amount of hyperplasia, dysplasia, angiogenesis, inflammatory foci, and goblet cells were then observed under the microscope. There is significant difference in the amount of dysplasia (p = 0.000) and angiogenesis (p = 0.009) among the groups that receive different concentrations of lunasin. However, there is no effect of lunasin administration to the amount of hyperplasia, inflammatory foci, and goblet cells. Nondose-dependent administration of lunasin extract improves dysplasia and angiogenesis, but not other factors in small intestine carcinogenesis.

Gastrointestinal longitudinal muscle contractions

1993 ◽  
Vol 265 (1) ◽  
pp. G156-G164 ◽  
Author(s):  
S. K. Sarna
Keyword(s):  
Small Intestine ◽  
Longitudinal Muscle ◽  
Circular Muscle ◽  
Muscle Contractions ◽  
Strongly Correlated ◽  
Elongation Complex ◽  
Fed State ◽  
Significant Difference ◽  
Enteric Nerves ◽  
Small Intestinal

The patterns of longitudinal muscle contractions of the stomach and the small intestine and their relationship with circular muscle contractions during the fasting and the fed state were investigated in conscious dogs. In the stomach, the longitudinal muscle contracted in a 1:1 relationship with the circular muscle contractions. There was no significant difference between the frequency, duration, and time of onset of gastric longitudinal and circular muscle contractions, and their amplitudes were significantly correlated with each other. In the small intestine when the circular muscle contracted, the longitudinal muscle exhibited passive elongation during the fasting and the fed state. There was no significant difference between the onset, duration, and frequency of small intestinal circular muscle contractions and the passive longitudinal muscle elongations; their amplitudes were strongly correlated with each other. During a circular muscle giant migrating contraction, the longitudinal muscle exhibited a monophasic contraction, initially a contraction followed by passive elongation or a pure passive elongation. During a retrograde giant contraction, the longitudinal muscle exhibited only a pure monophasic contraction or a contraction-elongation complex. These data suggest that the enteric nerves in the small intestine innervate the two muscle layers in a reciprocal fashion and those in the stomach in a complementary fashion.

scholarly journals Small intestinal damage associated with the use of nonsteroidal anti-inflammatory drugs

2019 ◽  
Vol 47 (6) ◽  
pp. 559-567 ◽  
Author(s):  
A. E. Karateev ◽  
E. V. Moroz ◽  
E. V. Kryukov
Keyword(s):  
Small Intestine ◽  
Capsule Endoscopy ◽  
Mucosal Inflammation ◽  
Intestinal Damage ◽  
Short Term ◽  
Iron Deficient ◽  
Nsaid Enteropathy ◽  
Inflammatory Drugs ◽  
Small Intestinal ◽  
Anti Inflammatory

The use of nonsteroidal anti-inflammatory drugs (NSAID), even if short-term, may be associated to small intestinal complications, such as erosions, ulcers and chronic mucosal inflammation. Video capsule endoscopy allows for identification of such lesions in 20 to 55% of the patients who have taken nonselective NSAID for 2 to 4  weeks. The pathophysiology of NSAID-induced enteropathy is related to a reduced reparative potential of the mucosa and abnormalities of the microbial balance in the small intestine. In real world practice, NSAID enteropathy is commonly asymptomatic, and its manifestations, such as bleeding, perforation and ileus, are quite rare (about 0.3 episodes per 100  patient-years). The main manifestation of NSAID enteropathy is chronic iron deficient anemia. The use of rebamipide, sulfasalazine, mesalazine, and rifaximin has been discussed in the treatment of NSAID enteropathy, whereas its prevention implies preferential administration of coxibs, the use of rebamipide and probiotics.

THE NEW GENERATION OF EXPRESS VIEW IS HIGHLY ACCURATE AND IS EFFECTIVE TO REDUCE CAPSULE ENDOSCOPY READING TIME

2020 ◽  
Author(s):  
S Piccirelli ◽  
A Mussetto ◽  
A Bellumat ◽  
R Cannizzaro ◽  
M Pennazio ◽  
...  
Keyword(s):  
Capsule Endoscopy ◽  
Reading Time ◽  
New Generation

LABORATORY TESTS OF THYROID FUNCTION IN HYPERTHYROIDISM II.

1969 ◽  
Vol 62 (4_Suppla) ◽  
pp. S23-S35
Author(s):  
B.-A. Lamberg ◽  
O. P. Heinonen ◽  
K. Liewendahl ◽  
G. Kvist ◽  
M. Viherkoski ◽  
...  
Keyword(s):  
Thyroid Function ◽  
Laboratory Tests ◽  
Goodness Of Fit ◽  
Point Of View ◽  
Accurate Estimation ◽  
Diagnostic Efficiency ◽  
Normal Limits ◽  
Significant Difference ◽  
Crossing Point ◽  
Hyperthyroid Patients

ABSTRACT The distributions of 13 variables based on 10 laboratory tests measuring thyroid function were studied in euthyroid controls and in patients with toxic diffuse or toxic multinodular goitre. Density functions were fitted to the empirical data and the goodness of fit was evaluated by the use of the χ2-test. In a few instances there was a significant difference but the material available was in some respects too small to allow a very accurate estimation. The normal limits for each variable was defined by the 2.5 and 97.5 percentiles. It appears that in some instances these limits are too rigorous from the practical point of view. It is emphasized that the crossing point of the functions for euthyroid controls and hyperthyroid patients may be a better limit to use. In a preliminary analysis of the diagnostic efficiency the variables of total or free hormone concentration in the blood proved clearily superior to all other variables.

Application of a dynamic mechanistic model of small intestinal starch digestion in the dairy cow

2002 ◽  
Vol 2002 ◽  
pp. 104-104
Author(s):  
J. A. N. Mills ◽  
E. Kebreab ◽  
L. A. Crompton ◽  
J. Dijkstra ◽  
J. France
Keyword(s):  
Experimental Data ◽  
Small Intestine ◽  
Dairy Cow ◽  
Energy Recovery ◽  
Mechanistic Model ◽  
Biological Knowledge ◽  
Dietary Energy ◽  
Starch Digestion ◽  
High Contribution ◽  
Small Intestinal

The high contribution of postruminal starch digestion (>50%) to total tract starch digestion on certain energy dense diets (Mills et al. 1999) demands that limitations to small intestinal starch digestion are identified. Therefore, a dynamic mechanistic model of the small intestine was constructed and evaluated against published experimental data for abomasal carbohydrate infusions in the dairy cow. The mechanistic structure of the model allowed the current biological knowledge to be integrated into a system capable of identifying restrictions to dietary energy recovery from postruminal starch delivery.

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