scholarly journals Marine Phytoplankton Improves Exercise Recovery in Humans and Activates Repair Mechanisms in Rats

Author(s):  
Matthew H. Sharp ◽  
Kazim Sahin ◽  
Matt W. Stefan ◽  
Raad H. Gheith ◽  
Dallen D. Reber ◽  
...  

AbstractThis study investigated the effects of marine phytoplankton supplementation on 1) perceived recovery and ground reaction forces in humans following a non-functional overreaching resistance-training program and 2) myogenic molecular markers associated with muscle cell recovery in a rat model. In the human trial, a 5-week resistance-training program with intentional overreaching on weeks 2 and 5 was implemented. Results indicate that marine phytoplankton prompted positive changes in perceived recovery at post-testing and, while both marine phytoplankton and placebo conditions demonstrated decreased peak and mean rate of force development following the overreaching weeks, placebo remained decreased at post-testing while marine phytoplankton returned to baseline levels. In the rat model, rats were divided into four conditions: (i) control, (ii) exercise, (iii) exercise + marine phytoplankton 2.55 mg·d-1, or (iv) exercise+marine phytoplankton 5.1 mg·d-1. Rats in exercising conditions performed treadmill exercise 5 d·wk-1 for 6 weeks. Marine phytoplankton in exercising rats increased positive and decrease negative myogenic factors regulating satellite cell proliferation. Taken together, marine phytoplankton improved perceptual and functional indices of exercise recovery in an overreaching human model and, mechanistically, this could be driven through cell cycle regulation and a potential to improve protein turnover.

Author(s):  
Ana Victoria Costa Freitas ◽  
Inês Amanda Streit ◽  
Josefina Bertoli ◽  
Kayth Andrade Nascimento ◽  
Maria Carolina Oliveira de Sá ◽  
...  

2017 ◽  
Vol 36 (12) ◽  
pp. 1331-1339 ◽  
Author(s):  
Alejandro Pérez-Castilla ◽  
Amador García-Ramos ◽  
Paulino Padial ◽  
Antonio J. Morales-Artacho ◽  
Belén Feriche

2021 ◽  
Author(s):  
Gabriela Souza de Vasconcelos ◽  
Guilherme Silva Nunes ◽  
Christian John Barton ◽  
Raquel Fantinelli Munhoz ◽  
Maria Eduarda Chinotti Batista da Silva ◽  
...  

Abstract Background: Strong evidence supports the proximal combined with quadriceps strengthening for patellofemoral pain (PFP) rehabilitation. However, most reported rehabilitation programs do not follow specific exercise prescription recommendations or do not provide adequate details for replication in clinical practice. Furthermore, people with PFP have power deficits in hip and knee muscles and remains unknown whether the addition of power exercises would result in superior or more consistent outcomes. Therefore, this study is designed to verify whether the benefits of a rehabilitation program addressing proximal and knee muscles composed by power and strength exercises are greater than those of a program composed by strength exercises only. Method: This study will be a randomized controlled trial, that will be conducted at university facilities. A minimum of 74 people with PFP between the ages of 18 and 45 years will be included. The experimental group will engage in a 12-week resistance training program focusing on proximal and knee muscles using power and strength exercises. The control group will engage in a 12-week resistance training program focusing on proximal and knee muscles using strength exercises only. Primary outcomes will be pain intensity and physical function; and secondary outcomes will be kinesiophobia, self-reported improvement, quality of life, peak hip and knee torque, and hip and knee rate of force development. The primary outcomes will be evaluated at baseline, and after six weeks, twelve weeks, three months, six months and one year. The secondary outcomes will be evaluated at baseline and immediately after the interventions. Therapists and participants will not be blinded to group allocation.Discussion: This randomized clinical trial will investigate if adding power exercises to a progressive resistance training may lead to more consistent outcomes for PFP rehabilitation. The study will provide additional knowledge to support rehabilitation programs for people with PFP.Trial registration: ClinicalTrials.gov NCT 03985254. Registered on 26 August 2019.


2014 ◽  
Vol 6 (1) ◽  
pp. 74-85 ◽  
Author(s):  
Anne Cabral ◽  
Íris Magalhães ◽  
Cláudio Borba-Pinheiro ◽  
Olavo Rocha-Júnior ◽  
Nébia Figueiredo ◽  
...  

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