Applications of the Horner-Wadsworth-Emmons olefination in modern natural product synthesis
Keyword(s):
Here, we have summarized more than 30 representative natural product syntheses published in 2015 to 2020 that employ one or more Horner-Wadsworth-Emmons (HWE) reactions. We comprehensively describe the applied phosphonate reagents, HWE reaction conditions and key steps of the total synthetic approaches. Our comprehensive review will support future synthetic approaches and serve as guideline to find the best HWE conditions for the most complicated natural products known
2021 ◽
Vol 16
(10)
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pp. 1934578X2110498
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2011 ◽
Vol 50
(5)
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pp. 1000-1045
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2022 ◽
2019 ◽
Vol 14
(10)
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pp. 1934578X1988440
2011 ◽
Vol 7
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pp. 1475-1485
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